protein

FGF20

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FGF20: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

111Connections

0Hypotheses

0Analyses

50Outgoing

43Incoming

Summary

FGF20 is a protein involved in neurodegeneration research. Key relationships include: therapeutic target, implicated in. Associated with Als, Cancer, Carcinoma. Connected to 85 entities in the SciDEX knowledge graph.

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🔬 Protein Info

Gene Symbol	FGF20
Full Name	Fibroblast Growth Factor 20
Chromosome	8p21.3
Function	FGF20 is a member of the FGF family of growth factors, which are involved in various developmental and regenerative processes.
Primary Expression	the brain, particularly in the substantia nigra
Molecular Weight	23 kDa
Pathways	PI3K, MAPK
UniProt ID	Q9NP95
NCBI Gene ID	56844
Ensembl ID	ENSG00000078579
OMIM	605830
GeneCards	FGF20
Human Protein Atlas	FGF20
Associated Diseases	neurodegeneration
KG Connections	111 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: FGF20 — AlphaFold Q9NP95 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (19)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    FGF20["FGF20"] -->|"therapeutic target"| Fibrosis["Fibrosis"]
    FGF20["FGF20"] -->|"therapeutic target"| Hepatitis["Hepatitis"]
    FGF20["FGF20"] -->|"therapeutic target"| Carcinoma["Carcinoma"]
    FGF20["FGF20"] -->|"therapeutic target"| Cancer["Cancer"]
    FGF20["FGF20"] -->|"therapeutic target"| Als["Als"]
    FGF20["FGF20"] -->|"therapeutic target"| Inflammation["Inflammation"]
    ALDH1A1["ALDH1A1"] -->|"therapeutic target"| FGF20["FGF20"]
    MITF["MITF"] -->|"therapeutic target"| FGF20["FGF20"]
    LEF1["LEF1"] -->|"therapeutic target"| FGF20["FGF20"]
    CANCER["CANCER"] -->|"therapeutic target"| FGF20["FGF20"]
    style FGF20 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (68)

Target	Relation	Type	Str
Fibrosis	therapeutic_target	disease	0.65
Hepatitis	therapeutic_target	disease	0.65
Carcinoma	therapeutic_target	disease	0.65
Cancer	therapeutic_target	disease	0.65
Als	therapeutic_target	disease	0.65
Inflammation	therapeutic_target	disease	0.65
Ms	therapeutic_target	disease	0.65
Prostate Cancer	therapeutic_target	disease	0.65
Infection	therapeutic_target	disease	0.65
Hepatocellular Carcinoma	therapeutic_target	disease	0.65
Colorectal Cancer	therapeutic_target	disease	0.65
Liver Cancer	therapeutic_target	disease	0.65
Pulmonary Fibrosis	therapeutic_target	disease	0.65
Lung Cancer	therapeutic_target	disease	0.65
Pancreatic Cancer	therapeutic_target	disease	0.65
Gastric Cancer	therapeutic_target	disease	0.65
BRG1	therapeutic_target	gene	0.60
NRCAM	therapeutic_target	gene	0.60
NOTCH2	therapeutic_target	gene	0.60
EP300	therapeutic_target	gene	0.60
CTNNB1	therapeutic_target	gene	0.60
NEUROD1	therapeutic_target	gene	0.60
MYC	therapeutic_target	gene	0.60
VEGFA	therapeutic_target	gene	0.60
ABCB1	therapeutic_target	gene	0.60
FOXM1	therapeutic_target	gene	0.60
LEF1	therapeutic_target	gene	0.60
SMARCA4	therapeutic_target	gene	0.60
TERT	therapeutic_target	gene	0.60
FZD7	therapeutic_target	gene	0.60
JAG1	therapeutic_target	gene	0.60
MITF	therapeutic_target	gene	0.60
GAIN	therapeutic_target	gene	0.60
AXIN2	therapeutic_target	gene	0.60
CD44	therapeutic_target	gene	0.60
ALDH1A1	therapeutic_target	gene	0.60
FGF18	therapeutic_target	gene	0.60
ATF3	therapeutic_target	gene	0.60
IL10	therapeutic_target	gene	0.60
DKK1	therapeutic_target	gene	0.60
PPARD	therapeutic_target	gene	0.60
CLDN1	therapeutic_target	gene	0.60
APC	therapeutic_target	gene	0.60
AXIN1	therapeutic_target	gene	0.60
PTGS2	therapeutic_target	gene	0.60
CREBBP	therapeutic_target	gene	0.60
FZD7	targets	gene	0.60
IL10	targets	gene	0.60
JAG1	targets	gene	0.60
LEF1	targets	gene	0.60

Incoming (43)

Source	Relation	Type	Str
ALDH1A1	therapeutic_target	gene	0.60
MITF	therapeutic_target	gene	0.60
LEF1	therapeutic_target	gene	0.60
ABCB1	therapeutic_target	gene	0.60
CLDN1	therapeutic_target	gene	0.60
JAG1	therapeutic_target	gene	0.60
CTNNB1	therapeutic_target	gene	0.60
AXIN1	therapeutic_target	gene	0.60
EP300	therapeutic_target	gene	0.60
BRG1	therapeutic_target	gene	0.60
CD44	therapeutic_target	gene	0.60
FGF18	therapeutic_target	gene	0.60
SMARCA4	therapeutic_target	gene	0.60
MYC	therapeutic_target	gene	0.60
NRCAM	therapeutic_target	gene	0.60
TERT	therapeutic_target	gene	0.60
NOTCH2	therapeutic_target	gene	0.60
PPARD	therapeutic_target	gene	0.60
NEUROD1	therapeutic_target	gene	0.60
APC	therapeutic_target	gene	0.60
CREBBP	therapeutic_target	gene	0.60
GAIN	therapeutic_target	gene	0.60
VEGFA	therapeutic_target	gene	0.60
IL10	therapeutic_target	gene	0.60
FZD7	therapeutic_target	gene	0.60
AXIN2	therapeutic_target	gene	0.60
ABCB1	targets	gene	0.60
ALDH1A1	targets	gene	0.60
ATF3	targets	gene	0.60
AXIN2	targets	gene	0.60
CD44	targets	gene	0.60
CLDN1	targets	gene	0.60
DKK1	targets	gene	0.60
FGF18	targets	gene	0.60
CANCER	therapeutic_target	gene	0.60
CDH1	therapeutic_target	gene	0.60
INFLAMMATION	therapeutic_target	gene	0.60
BAMBI	therapeutic_target	gene	0.60
GENES	therapeutic_target	gene	0.60
BAMBI	targets	gene	0.60
CCND1	targets	gene	0.60
CTLA4	targets	gene	0.60
EOMES	targets	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

FGF20

Understanding Entity Pages

Summary

Wiki Pages (19)

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Growth Factor Signaling in 4R-Tauopathies

PD FGF/FGFR Signaling Companies

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Intermediate Progenitor Cells

Growth Factor Therapies for Neurodegeneration

FGF20 Protein