concept

BAMBI

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BAMBI: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

148Connections
0Hypotheses
0Analyses
50Outgoing
50Incoming

Summary

BAMBI is a concept in neurodegeneration research. Key relationships include: therapeutic target, regulates, inhibits. Associated with Als, Cancer, Carcinoma. Connected to 98 entities in the SciDEX knowledge graph.

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💡 Concept Info
NameBAMBI
Key Genes/ProteinsPPARGC1A, ACSL5
Related DiseasesCarcinoma, Ms, Fibrosis, Hepatitis, Cancer
Related PathwaysTGF-β/SMAD Signaling

Wiki Pages (2)

Knowledge base pages for this entity

Activin A Receptor Type 1B (ACVR1B)

gene · 1933 words

PPARGC1A Gene

gene · 742 words

Pathway Diagram

graph TD
    BAMBI["BAMBI"]
    BAMBI -->|"regulates"| ACSL5["ACSL5"]
    BAMBI -->|"activates"| Carcinoma["Carcinoma"]
    BAMBI -->|"inhibits"| Ms["Ms"]
    BAMBI -->|"target for"| Fibrosis["Fibrosis"]
    BAMBI -->|"target for"| Hepatitis["Hepatitis"]
    BAMBI -->|"target for"| Cancer["Cancer"]
    BAMBI -->|"target for"| Als["Als"]
    BAMBI -->|"target for"| Inflammation["Inflammation"]
    PPARGC1A["PPARGC1A"] -->|"inhibits"| BAMBI
    WTAP["WTAP"] -->|"inhibits"| BAMBI
    ACSL5 -->|"regulates"| BAMBI
    FGF20["FGF20"] -->|"target for"| BAMBI
    BRG1["BRG1"] -->|"target for"| BAMBI
    NRCAM["NRCAM"] -->|"target for"| BAMBI
    NOTCH2["NOTCH2"] -->|"target for"| BAMBI
    EP300["EP300"] -->|"target for"| BAMBI
    CTNNB1["CTNNB1"] -->|"target for"| BAMBI
    NEUROD1["NEUROD1"] -->|"target for"| BAMBI

Outgoing (95)

TargetRelationTypeStr
TGF-β/SMAD Signalinginvolved_inpathway0.80
ACSL5regulatesgene0.72
Carcinomaactivatesdisease0.65
Msinhibitsdisease0.65
Fibrosistherapeutic_targetdisease0.65

Incoming (53)

SourceRelationTypeStr
PPARGC1Arepressesgene0.80
PPARGC1Ainhibitsgene0.72
WTAPinhibitsgene0.60
ACSL5regulatesgene0.60
FGF20therapeutic_targetgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found