NAIP

Understanding Entity Pages

This page aggregates everything SciDEX knows about NAIP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

NAIP (NLR Apoptosis Inhibitor Protein): NLR family protein involved in innate immunity, inflammasome activation, and cell death regulation. Implicated in ALS, SMA, and neurodegenerative diseases.

View on Wiki →

graph TD
    NAIP["<b>NAIP</b>"]
    Dementia{"Dementia"}
    NAIP -->|"associated with"| Dementia
    Inflammation{"Inflammation"}
    NAIP -->|"associated with"| Inflammation
    Metabolic_Syndrome{"Metabolic Syndrome"}
    NAIP -->|"interacts with"| Metabolic_Syndrome
    Cardiovascular{"Cardiovascular"}
    NAIP -->|"interacts with"| Cardiovascular
    NAIP -->|"interacts with"| Inflammation
    Als{"Als"}
    NAIP -->|"interacts with"| Als
    Ms{"Ms"}
    NAIP -->|"interacts with"| Ms
    CYTOKINES["CYTOKINES"]
    NAIP -->|"expressed in"| CYTOKINES
    PROINFLAMMATORY_CYTOKINES["PROINFLAMMATORY CYTOKINES"]
    NAIP -->|"expressed in"| PROINFLAMMATORY_CYTOKINES
    TNF["TNF"]
    NAIP -->|"expressed in"| TNF
    INFLAMMATION["INFLAMMATION"]
    NAIP -->|"associated with"| INFLAMMATION
    TNF__["TNF-Alpha"]
    NAIP -->|"expressed in"| TNF__
    PYCARD["PYCARD"]
    PYCARD -->|"expressed in"| NAIP
    PHAGOCYTOSIS["PHAGOCYTOSIS"]
    PHAGOCYTOSIS -->|"interacts with"| NAIP
    style NAIP fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0