concept

NANOG

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NANOG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

67Connections

0Hypotheses

0Analyses

46Outgoing

19Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	NANOG
Key Genes/Proteins	AND, SOX2, DAX1, ALZHEIMER
Related Diseases	Alzheimer'S Disease, Alzheimer, Aging, Senescence, Als
Related Pathways	Neurogenesis

Wiki Pages (9)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    NANOG["NANOG"]
    NANOG -->|"involved_in"| Pluripotency["Pluripotency"]
    NANOG -->|"expressed in"| Alzheimer["Alzheimer"]
    NANOG -->|"expressed in"| Aging["Aging"]
    NANOG -->|"expressed in"| Senescence["Senescence"]
    NANOG -->|"target for"| Als["Als"]
    NANOG -->|"target for"| Cancer["Cancer"]
    Melatonin["Melatonin"] -->|"upregulates"| NANOG
    SOX2["SOX2"] -->|"interacts"| NANOG
    ALZHEIMER["ALZHEIMER"] -->|"expressed in"| NANOG
    AGING["AGING"] -->|"expressed in"| NANOG
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"expressed in"| NANOG
    OCT4["OCT4"] -->|"interacts"| NANOG

Outgoing (47)

Target	Relation	Type	Str
Pluripotency	involved_in	process	0.90
Alzheimer'S Disease	involved_in	disease	0.80
Alzheimer	expressed_in	disease	0.65
Aging	expressed_in	disease	0.65
Senescence	expressed_in	disease	0.65
Alzheimer	regulates	disease	0.65
Aging	regulates	disease	0.65
Als	therapeutic_target	disease	0.65
Cancer	therapeutic_target	disease	0.65
AND	interacts_with	gene	0.60
SOX2	interacts_with	gene	0.60
Neurogenesis	expressed_in	pathway	0.60
SOX2	regulates	gene	0.60
DAX1	regulates	gene	0.60
ALZHEIMER	regulates	gene	0.60
KLF4	regulates	gene	0.60
AND	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
OCT4	regulates	gene	0.60
MIRNAS	regulates	gene	0.60
Epigenetic	regulates	pathway	0.60
Neurogenesis	regulates	pathway	0.60
ALZHEIMER	expressed_in	gene	0.60
ALZHEIMER'S DISEASE	expressed_in	gene	0.60
OCT4	interacts_with	gene	0.60
AGING	regulates	gene	0.60
Stem Cell	regulates	cell_type	0.60
AGING	expressed_in	gene	0.60
Stem Cell	interacts_with	cell_type	0.60
AKT	therapeutic_target	gene	0.60
NOTCH	interacts_with	gene	0.60
Mapk	therapeutic_target	pathway	0.60
Wnt	therapeutic_target	pathway	0.60
Notch	interacts_with	pathway	0.60
PERK	causes	gene	0.60
ERK1/2	activates	gene	0.60
Stem Cell	activates	cell_type	0.60
T Cell	activates	cell_type	0.60
OCT4	encodes	gene	0.60
Stem Cell	encodes	cell_type	0.60
App	expressed_in	protein	0.60
OCT4	activates	gene	0.60
POU5F1	activates	gene	0.60
epigenetic regulation	participates_in	pathway	0.60
Stem Cell	expressed_in	cell_type	0.55
Fibroblast	expressed_in	cell_type	0.55

Incoming (20)

Source	Relation	Type	Str
SOX2	interacts_with	gene	0.90
ALZHEIMER	expressed_in	gene	0.60
AGING	expressed_in	gene	0.60
ALZHEIMER'S DISEASE	expressed_in	gene	0.60
OCT4	interacts_with	gene	0.60
AGING	regulates	gene	0.60
ALZHEIMER	regulates	gene	0.60
WNT	therapeutic_target	gene	0.60
ERK	activates	gene	0.60
OCT4	causes	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
KLF4	regulates	gene	0.60
MIRNAS	regulates	gene	0.60
SOX2	regulates	gene	0.60
SOX2	encodes	gene	0.60
DAX1	regulates	gene	0.60
OCT4	regulates	gene	0.60
HDAC9	activates	gene	0.60
KDR	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

NANOG

Understanding Entity Pages

Wiki Pages (9)

YAP/TAZ Signaling Pathway in Neurodegeneration

WNT2B Gene - Wnt Family Member 2B

Induced Pluripotent Stem Cell (iPSC) Disease Models

MELK Gene

CHD1 Protein

SOX2 Protein

POU5F1 (Oct4) - POU Class 5 Homeobox 1