KDR

Understanding Entity Pages

This page aggregates everything SciDEX knows about KDR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

KDR (VEGFR2) - Kinase Insert Domain Receptor regulating angiogenesis, neurovascular coupling, and neurodegeneration

View on Wiki →

graph TD
    KDR["<b>KDR</b>"]
    Inflammation{"Inflammation"}
    KDR -->|"therapeutic target"| Inflammation
    Ms{"Ms"}
    KDR -->|"therapeutic target"| Ms
    Fibrosis{"Fibrosis"}
    KDR -->|"biomarker for"| Fibrosis
    Diabetes{"Diabetes"}
    KDR -->|"biomarker for"| Diabetes
    Als{"Als"}
    KDR -->|"biomarker for"| Als
    KDR -->|"biomarker for"| Ms
    MMP9["MMP9"]
    KDR -->|"inhibits"| MMP9
    ICAM1["ICAM1"]
    KDR -->|"inhibits"| ICAM1
    SPP1["SPP1"]
    KDR -->|"inhibits"| SPP1
    Angiogenesis(["Angiogenesis"])
    KDR -->|"inhibits"| Angiogenesis
    MMP2["MMP2"]
    KDR -->|"inhibits"| MMP2
    NOS2["NOS2"]
    KDR -->|"inhibits"| NOS2
    RAGE["RAGE"]
    RAGE -->|"therapeutic target"| KDR
    SERPINE1["SERPINE1"]
    SERPINE1 -->|"inhibits"| KDR
    NOS2 -->|"inhibits"| KDR
    MMP2 -->|"inhibits"| KDR
    PTGS2["PTGS2"]
    PTGS2 -->|"inhibits"| KDR
    ICAM1 -->|"inhibits"| KDR
    MMP9 -->|"inhibits"| KDR
    CYTOKINES["CYTOKINES"]
    CYTOKINES -->|"therapeutic target"| KDR
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"therapeutic target"| KDR
    CD44["CD44"]
    CD44 -->|"biomarker for"| KDR
    IGF1["IGF1"]
    IGF1 -->|"biomarker for"| KDR
    EGF["EGF"]
    EGF -->|"biomarker for"| KDR
    style KDR fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0