P2RX3

Understanding Entity Pages

This page aggregates everything SciDEX knows about P2RX3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

P2RX3 is a gene implicated in neurodegeneration research. Key relationships include: regulates, activates, implicated in. Associated with Aging, Inflammation, Ms. Connected to 31 entities in the SciDEX knowledge graph.

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graph TD
    P2RX3["<b>P2RX3</b>"]
    Inflammation{"Inflammation"}
    P2RX3 -->|"activates"| Inflammation
    Aging{"Aging"}
    P2RX3 -->|"activates"| Aging
    Ms{"Ms"}
    P2RX3 -->|"activates"| Ms
    RELA["RELA"]
    P2RX3 -->|"regulates"| RELA
    SYP["SYP"]
    P2RX3 -->|"regulates"| SYP
    CHRNA7["CHRNA7"]
    P2RX3 -->|"regulates"| CHRNA7
    SYT1["SYT1"]
    P2RX3 -->|"regulates"| SYT1
    STAT3["STAT3"]
    P2RX3 -->|"regulates"| STAT3
    HMOX1["HMOX1"]
    P2RX3 -->|"regulates"| HMOX1
    TRPV1["TRPV1"]
    P2RX3 -->|"regulates"| TRPV1
    P2RY2["P2RY2"]
    P2RX3 -->|"regulates"| P2RY2
    FOXP3["FOXP3"]
    P2RX3 -->|"regulates"| FOXP3
    PANX1["PANX1"]
    PANX1 -->|"regulates"| P2RX3
    S100B["S100B"]
    S100B -->|"regulates"| P2RX3
    RELB["RELB"]
    RELB -->|"regulates"| P2RX3
    P2RY1["P2RY1"]
    P2RY1 -->|"regulates"| P2RX3
    CASP3["CASP3"]
    CASP3 -->|"regulates"| P2RX3
    SOCS3["SOCS3"]
    SOCS3 -->|"regulates"| P2RX3
    TRPA1["TRPA1"]
    TRPA1 -->|"regulates"| P2RX3
    GENES["GENES"]
    GENES -->|"regulates"| P2RX3
    CXCL2["CXCL2"]
    CXCL2 -->|"regulates"| P2RX3
    SNAP25["SNAP25"]
    SNAP25 -->|"regulates"| P2RX3
    P2RX7["P2RX7"]
    P2RX7 -->|"regulates"| P2RX3
    SYT2["SYT2"]
    SYT2 -->|"regulates"| P2RX3
    style P2RX3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0