PANX1

Understanding Entity Pages

This page aggregates everything SciDEX knows about PANX1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PANX1 is a gene implicated in neurodegeneration research. Key relationships include: regulates, activates, associated with. Associated with ALS, Aging, Als. Connected to 62 entities in the SciDEX knowledge graph.

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graph TD
    PANX1["<b>PANX1</b>"]
    Als{"Als"}
    PANX1 -->|"associated with"| Als
    Inflammation{"Inflammation"}
    PANX1 -->|"associated with"| Inflammation
    Ms{"Ms"}
    PANX1 -->|"activates"| Ms
    PANX1 -->|"activates"| Als
    PANX1 -->|"activates"| Inflammation
    Aging{"Aging"}
    PANX1 -->|"activates"| Aging
    Covid{"Covid"}
    PANX1 -->|"activates"| Covid
    ALS{"ALS"}
    PANX1 -->|"associated with"| ALS
    P2X7["P2X7"]
    PANX1 -->|"activates"| P2X7
    SRC["SRC"]
    PANX1 -->|"activates"| SRC
    GENES["GENES"]
    PANX1 -->|"activates"| GENES
    P2RX1["P2RX1"]
    PANX1 -->|"activates"| P2RX1
    ADORA2B["ADORA2B"]
    ADORA2B -->|"activates"| PANX1
    P2RY12["P2RY12"]
    P2RY12 -->|"activates"| PANX1
    P2RX1 -->|"activates"| PANX1
    P2RX4["P2RX4"]
    P2RX4 -->|"activates"| PANX1
    P2RX7["P2RX7"]
    P2RX7 -->|"activates"| PANX1
    CD38["CD38"]
    CD38 -->|"associated with"| PANX1
    P2RY1["P2RY1"]
    P2RY1 -->|"activates"| PANX1
    P2RX5["P2RX5"]
    P2RX5 -->|"activates"| PANX1
    ATP["ATP"]
    ATP -->|"associated with"| PANX1
    NAD["NAD"]
    NAD -->|"associated with"| PANX1
    GENES -->|"activates"| PANX1
    AND["AND"]
    AND -->|"activates"| PANX1
    style PANX1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0