PRDX5

Understanding Entity Pages

This page aggregates everything SciDEX knows about PRDX5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PRDX5 is a gene implicated in neurodegeneration research. Key relationships include: activates, expressed in, associated with. Associated with Als, Cancer, Fibrosis. Connected to 17 entities in the SciDEX knowledge graph.

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graph TD
    PRDX5["<b>PRDX5</b>"]
    Als{"Als"}
    PRDX5 -->|"expressed in"| Als
    Cancer{"Cancer"}
    PRDX5 -->|"inhibits"| Cancer
    Fibrosis{"Fibrosis"}
    PRDX5 -->|"activates"| Fibrosis
    PRDX5 -->|"activates"| Als
    Hepatitis{"Hepatitis"}
    PRDX5 -->|"activates"| Hepatitis
    Ms{"Ms"}
    PRDX5 -->|"therapeutic target"| Ms
    CTSD["CTSD"]
    PRDX5 -->|"associated with"| CTSD
    Akt(["Akt"])
    PRDX5 -->|"expressed in"| Akt
    OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    PRDX5 -->|"activates"| OXIDATIVE_STRESS
    Oxidative_Stress(["Oxidative Stress"])
    PRDX5 -->|"activates"| Oxidative_Stress
    neurodegeneration["neurodegeneration"]
    PRDX5 -->|"implicated in"| neurodegeneration
    GABPB1["GABPB1"]
    GABPB1 -->|"upregulates"| PRDX5
    CALR["CALR"]
    CALR -->|"associated with"| PRDX5
    S100A6["S100A6"]
    S100A6 -->|"associated with"| PRDX5
    AKT["AKT"]
    AKT -->|"expressed in"| PRDX5
    CANCER["CANCER"]
    CANCER -->|"inhibits"| PRDX5
    EGF["EGF"]
    EGF -->|"activates"| PRDX5
    style PRDX5 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0