PRKCB

Understanding Entity Pages

This page aggregates everything SciDEX knows about PRKCB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PRKCB is a gene implicated in neurodegeneration research. Key relationships include: expressed in, associated with, therapeutic target. Associated with Als, Alzheimer, Cancer. Connected to 38 entities in the SciDEX knowledge graph.

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graph TD
    PRKCB["<b>PRKCB</b>"]
    Alzheimer{"Alzheimer"}
    PRKCB -->|"associated with"| Alzheimer
    Als{"Als"}
    PRKCB -->|"activates"| Als
    Tumor{"Tumor"}
    PRKCB -->|"activates"| Tumor
    Senescence{"Senescence"}
    PRKCB -->|"expressed in"| Senescence
    Ms{"Ms"}
    PRKCB -->|"associated with"| Ms
    Dementia{"Dementia"}
    PRKCB -->|"associated with"| Dementia
    PRKCB -->|"associated with"| Als
    PRKCB -->|"therapeutic target"| Ms
    Cancer{"Cancer"}
    PRKCB -->|"therapeutic target"| Cancer
    PRKCB -->|"associated with"| Cancer
    PRKCB -->|"associated with"| Tumor
    C3["C3"]
    PRKCB -->|"activates"| C3
    BIN1["BIN1"]
    BIN1 -->|"expressed in"| PRKCB
    CDKN2A["CDKN2A"]
    CDKN2A -->|"expressed in"| PRKCB
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    NEURODEGENERATIVE_DISEASES -->|"expressed in"| PRKCB
    ALZHEIMER_DISEASE["ALZHEIMER DISEASE"]
    ALZHEIMER_DISEASE -->|"associated with"| PRKCB
    MAPK3["MAPK3"]
    MAPK3 -->|"therapeutic target"| PRKCB
    CDK6["CDK6"]
    CDK6 -->|"therapeutic target"| PRKCB
    EP300["EP300"]
    EP300 -->|"associated with"| PRKCB
    IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
    IMMUNE_INFILTRATION -->|"associated with"| PRKCB
    CANCER["CANCER"]
    CANCER -->|"associated with"| PRKCB
    BST2["BST2"]
    BST2 -->|"activates"| PRKCB
    style PRKCB fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0