PTBP1

Understanding Entity Pages

This page aggregates everything SciDEX knows about PTBP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PTBP1 (Polypyrimidine Tract Binding Protein 1) - RNA binding protein regulating alternative splicing in neurodegeneration

View on Wiki →

graph TD
    PTBP1["<b>PTBP1</b>"]
    Ms{"Ms"}
    PTBP1 -->|"activates"| Ms
    Als{"Als"}
    PTBP1 -->|"activates"| Als
    PTBP1 -->|"associated with"| Als
    Ischemia{"Ischemia"}
    PTBP1 -->|"protects against"| Ischemia
    PTBP1 -->|"inhibits"| Ms
    Stroke{"Stroke"}
    PTBP1 -->|"inhibits"| Stroke
    Cancer{"Cancer"}
    PTBP1 -->|"activates"| Cancer
    PTBP1 -->|"interacts with"| Als
    Hepatitis{"Hepatitis"}
    PTBP1 -->|"interacts with"| Hepatitis
    PTBP1 -->|"interacts with"| Ms
    Carcinoma{"Carcinoma"}
    PTBP1 -->|"interacts with"| Carcinoma
    Tumor{"Tumor"}
    PTBP1 -->|"inhibits"| Tumor
    ATG["ATG"]
    ATG -->|"activates"| PTBP1
    HNRNPA1["HNRNPA1"]
    HNRNPA1 -->|"expressed in"| PTBP1
    CALCOCO2["CALCOCO2"]
    CALCOCO2 -->|"activates"| PTBP1
    TARDBP["TARDBP"]
    TARDBP -->|"expressed in"| PTBP1
    NDP52["NDP52"]
    NDP52 -->|"activates"| PTBP1
    ATG -->|"associated with"| PTBP1
    CALCOCO2 -->|"associated with"| PTBP1
    EGR1["EGR1"]
    EGR1 -->|"associated with"| PTBP1
    GSS["GSS"]
    GSS -->|"activates"| PTBP1
    CANCER["CANCER"]
    CANCER -->|"activates"| PTBP1
    AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"activates"| PTBP1
    ATG5["ATG5"]
    ATG5 -->|"activates"| PTBP1
    style PTBP1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0