SUCLG1

Understanding Entity Pages

This page aggregates everything SciDEX knows about SUCLG1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

α subunit of succinyl-CoA synthetase essential for TCA cycle and mitochondrial GTP synthesis

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graph TD
    SUCLG1["<b>SUCLG1</b>"]
    Ischemia{"Ischemia"}
    SUCLG1 -->|"regulates"| Ischemia
    Ms{"Ms"}
    SUCLG1 -->|"therapeutic target"| Ms
    Cardiac{"Cardiac"}
    SUCLG1 -->|"regulates"| Cardiac
    Inflammation{"Inflammation"}
    SUCLG1 -->|"regulates"| Inflammation
    Alzheimer{"Alzheimer"}
    SUCLG1 -->|"inhibits"| Alzheimer
    Als{"Als"}
    SUCLG1 -->|"activates"| Als
    SUCLG1 -->|"expressed in"| Ms
    GAIN["GAIN"]
    SUCLG1 -->|"regulates"| GAIN
    TLR4["TLR4"]
    SUCLG1 -->|"regulates"| TLR4
    Immune_Response(["Immune Response"])
    SUCLG1 -->|"regulates"| Immune_Response
    Nf__b(["Nf-Kappab"])
    SUCLG1 -->|"regulates"| Nf__b
    Apoptosis(["Apoptosis"])
    SUCLG1 -->|"regulates"| Apoptosis
    __HYDROXYBUTYRATE["Beta-HYDROXYBUTYRATE"]
    __HYDROXYBUTYRATE -->|"activates"| SUCLG1
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"inhibits"| SUCLG1
    APP_PS1["APP/PS1"]
    APP_PS1 -->|"inhibits"| SUCLG1
    APP["APP"]
    APP -->|"inhibits"| SUCLG1
    style SUCLG1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0