gene

SYNGR1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYNGR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

82Connections
0Hypotheses
0Analyses
41Outgoing
41Incoming

Summary

SYNGR1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, implicated in. Associated with ALS, Als, Bipolar. Connected to 51 entities in the SciDEX knowledge graph.

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🧬 Gene Info
Gene SymbolSYNGR1
Full NameSynaptogyrin 1
Chromosome22q12-q13 region
Functionis an important component in the neurobiology of neurodegenerative diseases.
NCBI Gene IDSYNGR1 Gene
Ensembl IDENSG00000185499
OMIM603171
GeneCardsSYNGR1
Human Protein AtlasSYNGR1
Full nameSynaptogyrin 1
Encoded proteinSYNGR1 Protein
Related pathwaysSynaptic Vesicle Trafficking, Protein Aggregation
Associated DiseasesALS, Bipolar, Depression, Ms, Schizophrenia
InteractionsGRIN2B, RGS4, NCAM1, DISC1, NRG1, GRM3
KG Connections82 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Wiki Pages (9)

Knowledge base pages for this entity

Canonical Page

SYNGR1 Gene

gene · 688 words

SYNAPTOGENIN — Synaptogyrin Family

gene · 2576 words

GRM4 Gene

gene · 1868 words

Synaptogyrin 1 Protein

protein · 903 words

Cerebellar Granule Cell Layer

cell · 836 words

RIM1 Gene

gene · 813 words

Pathway Diagram

graph TD
    SYNGR1["<b>SYNGR1</b>"]
    Schizophrenia{"Schizophrenia"}
    SYNGR1 -->|"associated with"| Schizophrenia
    Als{"Als"}
    SYNGR1 -->|"associated with"| Als
    Depression{"Depression"}
    SYNGR1 -->|"associated with"| Depression
    Bipolar{"Bipolar"}
    SYNGR1 -->|"associated with"| Bipolar
    Ms{"Ms"}
    SYNGR1 -->|"associated with"| Ms
    ALS{"ALS"}
    SYNGR1 -->|"associated with"| ALS
    BDNF["BDNF"]
    SYNGR1 -->|"associated with"| BDNF
    NCAM1["NCAM1"]
    SYNGR1 -->|"associated with"| NCAM1
    RGS4["RGS4"]
    SYNGR1 -->|"associated with"| RGS4
    GRIN2B["GRIN2B"]
    SYNGR1 -->|"associated with"| GRIN2B
    DRD1["DRD1"]
    SYNGR1 -->|"associated with"| DRD1
    TPH2["TPH2"]
    SYNGR1 -->|"associated with"| TPH2
    HTR2A["HTR2A"]
    HTR2A -->|"associated with"| SYNGR1
    DISC1["DISC1"]
    DISC1 -->|"associated with"| SYNGR1
    FKBP5["FKBP5"]
    FKBP5 -->|"associated with"| SYNGR1
    NRG1["NRG1"]
    NRG1 -->|"associated with"| SYNGR1
    DAO["DAO"]
    DAO -->|"associated with"| SYNGR1
    BMAL1["BMAL1"]
    BMAL1 -->|"associated with"| SYNGR1
    GRM4["GRM4"]
    GRM4 -->|"associated with"| SYNGR1
    HTTLPR["HTTLPR"]
    HTTLPR -->|"associated with"| SYNGR1
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"]
    MITOCHONDRIAL_DNA -->|"associated with"| SYNGR1
    BDNF -->|"associated with"| SYNGR1
    PERIOD3["PERIOD3"]
    PERIOD3 -->|"associated with"| SYNGR1
    G72["G72"]
    G72 -->|"associated with"| SYNGR1
    style SYNGR1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (41)

TargetRelationTypeStr
Schizophreniaassociated_withdisease0.65
Alsassociated_withdisease0.65
Depressionassociated_withdisease0.65
Bipolarassociated_withdisease0.65
Msassociated_withdisease0.65

Incoming (41)

SourceRelationTypeStr
HTR2Aassociated_withgene0.60
DISC1associated_withgene0.60
FKBP5associated_withgene0.60
NRG1associated_withgene0.60
DAOassociated_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found