Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about UBIQUITINATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | UBIQUITINATION |
| Key Genes/Proteins | USP7, UBIQUITIN, UBIQUITIN_LIGASES |
| Related Pathways | DIA_MS |
Knowledge base pages for this entity
graph TD
UBIQUITINATION["UBIQUITINATION"]
UBIQUITINATION -->|"modulates"| G3BP1["G3BP1"]
UBIQUITINATION -->|"regulates"| Protein_Stability["Protein Stability"]
UBIQUITINATION -->|"mediates"| NLRP3["NLRP3"]
UBIQUITINATION -->|"modulates"| TDP_43["TDP-43"]
UBIQUITINATION -->|"regulates"| ATG5["ATG5"]
UBIQUITINATION -->|"involved_in"| NLRP3_Autophagy_Degradation["NLRP3 Autophagy Degradation"]
USP7["USP7"] -->|"regulates"| UBIQUITINATION
PEDV_N["PEDV N"] -->|"involved_in"| UBIQUITINATION
ubiquitin_ligases["ubiquitin ligases"] -->|"activates"| UBIQUITINATION
deubiquitinases["deubiquitinases"] -->|"inhibits"| UBIQUITINATION
MARCH2["MARCH2"] -->|"regulates"| UBIQUITINATION
UBIQUITIN_LIGASES["UBIQUITIN LIGASES"] -->|"catalyzes"| UBIQUITINATION
__SYNUCLEIN["Alpha-SYNUCLEIN"] -->|"involved_in"| UBIQUITINATION
DUBS["DUBS"] -->|"regulates"| UBIQUITINATION| Target | Relation | Type | Str |
|---|---|---|---|
| G3BP1 | modulates | entity | 0.95 |
| Source | Relation | Type | Str |
|---|---|---|---|
| USP7 | regulates | protein | 0.72 |
| UBIQUITIN | participates_in | protein | 0.72 |
| UBIQUITIN_LIGASES | catalyzes | protein | 0.64 |
| DIA_MS | regulates | pathway | 0.56 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-08 | 0 hypotheses
neurodegeneration | 2026-04-07 | 0 hypotheses
neurodegeneration | 2026-04-06 | 0 hypotheses
neurodegeneration | 2026-04-04 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||