concept

UBIQUITINATION

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about UBIQUITINATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

99Connections
0Hypotheses
4Analyses
1Outgoing
4Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameUBIQUITINATION
Key Genes/ProteinsUSP7, UBIQUITIN, UBIQUITIN_LIGASES
Related PathwaysDIA_MS

Wiki Pages (20)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery Alternatives

therapeutic · 15567 words

Progressive Supranuclear Palsy (PSP)

disease · 12907 words

Novel Therapy Index

idea · 10647 words

Parkinson's Disease

disease · 8807 words

Pathway Diagram

graph TD
    UBIQUITINATION["UBIQUITINATION"]
    UBIQUITINATION -->|"modulates"| G3BP1["G3BP1"]
    UBIQUITINATION -->|"regulates"| Protein_Stability["Protein Stability"]
    UBIQUITINATION -->|"mediates"| NLRP3["NLRP3"]
    UBIQUITINATION -->|"modulates"| TDP_43["TDP-43"]
    UBIQUITINATION -->|"regulates"| ATG5["ATG5"]
    UBIQUITINATION -->|"involved_in"| NLRP3_Autophagy_Degradation["NLRP3 Autophagy Degradation"]
    USP7["USP7"] -->|"regulates"| UBIQUITINATION
    PEDV_N["PEDV N"] -->|"involved_in"| UBIQUITINATION
    ubiquitin_ligases["ubiquitin ligases"] -->|"activates"| UBIQUITINATION
    deubiquitinases["deubiquitinases"] -->|"inhibits"| UBIQUITINATION
    MARCH2["MARCH2"] -->|"regulates"| UBIQUITINATION
    UBIQUITIN_LIGASES["UBIQUITIN LIGASES"] -->|"catalyzes"| UBIQUITINATION
    __SYNUCLEIN["Alpha-SYNUCLEIN"] -->|"involved_in"| UBIQUITINATION
    DUBS["DUBS"] -->|"regulates"| UBIQUITINATION

Outgoing (30)

TargetRelationTypeStr
G3BP1modulatesentity0.95

Incoming (69)

SourceRelationTypeStr
USP7regulatesprotein0.72
UBIQUITINparticipates_inprotein0.72
UBIQUITIN_LIGASEScatalyzesprotein0.64
DIA_MSregulatespathway0.56

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (4)

Scientific analyses that reference this entity

What determines the spatial organization of autophagy receptors at stress granul

neurodegeneration | 2026-04-08 | 0 hypotheses

How does TRIM21-mediated K63 ubiquitination of G3BP1 mechanistically inhibit liq

neurodegeneration | 2026-04-07 | 0 hypotheses

How do pathological stress granules in neurodegeneration escape TRIM21/autophagy

neurodegeneration | 2026-04-06 | 0 hypotheses

Quantitative proteomics of the aging synapse in early Alzheimer disease

neurodegeneration | 2026-04-04 | 0 hypotheses

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found