| Gene Symbol | BECN1 |
| Function | BECN1 encodes beclin-1, a key regulator of autophagy—a cellular process for degrading and recycling damaged organelles, protein aggregates, and intracellular pathogens. |
| Molecular Weight | 60 kDa |
| Pathways | Akt, Apoptosis, Autophagy, Car-T, Epigenetic |
| UniProt ID | Q9Y5P6 |
| Ensembl ID | ENSG00000126581 |
| GeneCards | BECN1 |
| Human Protein Atlas | BECN1 |
| Autophagosome Maturation | Recruits ATG proteins and facilitates membrane closure |
| Endocytic Trafficking | Regulates endocytic pathway and vacuolar protein sorting |
| Tumor Suppression | Functions as a haploinsufficient tumor suppressor |
| Associated Diseases | AD, ALI, Als, Alzheimer, Alzheimer's disease |
| Known Drugs/Compounds | crocin, HCQ, Isorhapontigenin, nicotine, rapamycin, RAPAMYCIN |
| Interactions | ABCD3, ACAT1, ACETYL-COA, ACHE, ACOX1, ACTB |
| KG Connections | 3054 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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