PRKDC

Understanding Entity Pages

This page aggregates everything SciDEX knows about PRKDC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for PRKDC — DNA-Dependent Protein Kinase Catalytic Subunit

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graph TD
    PRKDC["<b>PRKDC</b>"]
    Glioblastoma{"Glioblastoma"}
    PRKDC -->|"inhibits"| Glioblastoma
    Tumor{"Tumor"}
    PRKDC -->|"associated with"| Tumor
    Cancer{"Cancer"}
    PRKDC -->|"activates"| Cancer
    Carcinoma{"Carcinoma"}
    PRKDC -->|"activates"| Carcinoma
    DRP1["DRP1"]
    PRKDC -->|"associated with"| DRP1
    GBM["GBM"]
    PRKDC -->|"associated with"| GBM
    Mitophagy(["Mitophagy"])
    PRKDC -->|"inhibits"| Mitophagy
    Oxidative_Phosphorylation(["Oxidative Phosphorylation"])
    PRKDC -->|"inhibits"| Oxidative_Phosphorylation
    DNM1L["DNM1L"]
    PRKDC -->|"associated with"| DNM1L
    FIS1["FIS1"]
    PRKDC -->|"associated with"| FIS1
    STK11["STK11"]
    PRKDC -->|"activates"| STK11
    ULK1["ULK1"]
    PRKDC -->|"regulates"| ULK1
    SOX2["SOX2"]
    SOX2 -->|"interacts with"| PRKDC
    DNM1L -->|"associated with"| PRKDC
    FIS1 -->|"associated with"| PRKDC
    MFF["MFF"]
    MFF -->|"associated with"| PRKDC
    DRP1 -->|"associated with"| PRKDC
    MITOPHAGY["MITOPHAGY"]
    MITOPHAGY -->|"inhibits"| PRKDC
    style PRKDC fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0