Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COMPLEMENT GENES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | COMPLEMENT GENES |
| Related Diseases | Cancer Prognosis, Prognosis, Poor Prognosis, Favorable Outcomes, Late-Onset Alzheimer's Disease |
Knowledge base pages for this entity
graph TD
COMPLEMENT_GENES["COMPLEMENT GENES"]
COMPLEMENT_GENES -->|"correlates_with"| Cancer_Prognosis["Cancer Prognosis"]
COMPLEMENT_GENES -->|"regulates"| Tumor["Tumor"]
COMPLEMENT_GENES -->|"regulates"| ALS["ALS"]
COMPLEMENT_GENES -->|"regulates"| Inflammation["Inflammation"]
COMPLEMENT_GENES -->|"regulates"| Phagocytosis["Phagocytosis"]
COMPLEMENT_GENES -->|"regulates"| INFLAMMATION["INFLAMMATION"]
COMPLEMENT_GENES -->|"regulates"| AND["AND"]
COMPLEMENT_GENES -->|"expressed in"| T_Cell["T Cell"]
C5AR1["C5AR1"] -->|"regulates"| COMPLEMENT_GENES
INFLAMMATION -->|"regulates"| COMPLEMENT_GENES
AND -->|"regulates"| COMPLEMENT_GENES| Target | Relation | Type | Str |
|---|---|---|---|
| Cancer Prognosis | correlates_with | phenotype | 0.90 |
| Prognosis | correlates_with | phenotype | 0.90 |
| Poor Prognosis | associated_with | phenotype | 0.85 |
| Favorable Outcomes | associated_with | phenotype | 0.85 |
| Late-Onset Alzheimer's Disease | risk_factor_for | disease | 0.85 |
| Neurodegeneration | associated_with | disease | 0.65 |
| Multiple Sclerosis | associated_with | disease | 0.65 |
| Aging | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| Tumor | regulates | disease | 0.65 |
| Cancer | associated_with | disease | 0.65 |
| ALS | regulates | disease | 0.65 |
| Inflammation | regulates | disease | 0.65 |
| Alzheimer | associated_with | disease | 0.65 |
| Senescence | associated_with | disease | 0.65 |
| C1QA | associated_with | gene | 0.60 |
| Complement | associated_with | pathway | 0.60 |
| CANCER | associated_with | gene | 0.60 |
| Phagocytosis | regulates | pathway | 0.60 |
| ALZHEIMER'S DISEASE | associated_with | gene | 0.60 |
| C1QB | associated_with | gene | 0.60 |
| SIRPA | associated_with | gene | 0.60 |
| ITGAM | associated_with | gene | 0.60 |
| NEURODEGENERATIVE DISORDERS | associated_with | gene | 0.60 |
| CR1 | associated_with | gene | 0.60 |
| AND | associated_with | gene | 0.60 |
| COMPLEMENT | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| INFLAMMATION | regulates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
| T Cell | expressed_in | cell_type | 0.55 |
| Microglia | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GENES | associated_with | gene | 0.60 |
| EARLY COMPLEMENT GENES | associated_with | gene | 0.60 |
| NEURODEGENERATION | associated_with | gene | 0.60 |
| COMPLEMENT | associated_with | gene | 0.60 |
| CR1 | associated_with | gene | 0.60 |
| AND | associated_with | gene | 0.60 |
| C5AR1 | regulates | gene | 0.60 |
| INFLAMMATION | regulates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
| AGING | associated_with | gene | 0.60 |
| C1QC | associated_with | gene | 0.60 |
| C1R | associated_with | gene | 0.60 |
| ALZHEIMER | associated_with | gene | 0.60 |
| CD47 | associated_with | gene | 0.60 |
| C1S | associated_with | gene | 0.60 |
| SYNAPTIC PRUNING | associated_with | gene | 0.60 |
| MERTK | associated_with | gene | 0.60 |
| C1QA | associated_with | gene | 0.60 |
| CANCER | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||