ITGAM

Understanding Entity Pages

This page aggregates everything SciDEX knows about ITGAM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ITGAM is a protein involved in neurodegeneration research. Key relationships include: activates, regulates, implicated in. Associated with Als, Cancer, Cardiac. Connected to 31 entities in the SciDEX knowledge graph.

View on Wiki →

graph TD
    ITGAM["<b>ITGAM</b>"]
    Ms{"Ms"}
    ITGAM -->|"activates"| Ms
    Cancer{"Cancer"}
    ITGAM -->|"activates"| Cancer
    Tumor{"Tumor"}
    ITGAM -->|"activates"| Tumor
    TNF["TNF"]
    ITGAM -->|"activates"| TNF
    NF__B["NF-KappaB"]
    ITGAM -->|"activates"| NF__B
    CXCL2["CXCL2"]
    ITGAM -->|"activates"| CXCL2
    CD14["CD14"]
    ITGAM -->|"activates"| CD14
    CANCER["CANCER"]
    ITGAM -->|"activates"| CANCER
    PPARG["PPARG"]
    ITGAM -->|"activates"| PPARG
    TNF__["TNF-Alpha"]
    ITGAM -->|"activates"| TNF__
    MSR1["MSR1"]
    ITGAM -->|"activates"| MSR1
    JUN["JUN"]
    ITGAM -->|"activates"| JUN
    ICAM1["ICAM1"]
    ICAM1 -->|"activates"| ITGAM
    TREM2["TREM2"]
    TREM2 -->|"activates"| ITGAM
    TLR2["TLR2"]
    TLR2 -->|"activates"| ITGAM
    NFKBIA["NFKBIA"]
    NFKBIA -->|"activates"| ITGAM
    MRC1["MRC1"]
    MRC1 -->|"activates"| ITGAM
    IL1B["IL1B"]
    IL1B -->|"activates"| ITGAM
    P53["P53"]
    P53 -->|"activates"| ITGAM
    style ITGAM fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0