C5AR1

Understanding Entity Pages

This page aggregates everything SciDEX knows about C5AR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

C5AR1 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, associated with, activates. Associated with Als, Alzheimer, Inflammation. Connected to 22 entities in the SciDEX knowledge graph.

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graph TD
    C5AR1["C5AR1"]
    Alzheimer{"Alzheimer"}
    C5AR1 -->|"therapeutic target"| Alzheimer
    Als{"Als"}
    C5AR1 -->|"activates"| Als
    Inflammation{"Inflammation"}
    C5AR1 -->|"activates"| Inflammation
    Ms{"Ms"}
    C5AR1 -->|"therapeutic target"| Ms
    TNF["TNF"]
    C5AR1 -->|"therapeutic target"| TNF
    INFLAMMATION["INFLAMMATION"]
    C5AR1 -->|"activates"| INFLAMMATION
    ZFP36["ZFP36"]
    C5AR1 -->|"expressed in"| ZFP36
    IL_6["IL-6"]
    C5AR1 -->|"therapeutic target"| IL_6
    HSPA1A["HSPA1A"]
    C5AR1 -->|"associated with"| HSPA1A
    HSPB1["HSPB1"]
    C5AR1 -->|"associated with"| HSPB1
    SERPINA3["SERPINA3"]
    C5AR1 -->|"expressed in"| SERPINA3
    PCK1["PCK1"]
    C5AR1 -->|"therapeutic target"| PCK1
    ICAM1["ICAM1"]
    ICAM1 -->|"associated with"| C5AR1
    CXCL1["CXCL1"]
    CXCL1 -->|"associated with"| C5AR1
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    NEURODEGENERATIVE_DISEASES -->|"therapeutic target"| C5AR1
    SOCS3["SOCS3"]
    SOCS3 -->|"associated with"| C5AR1
    IL6["IL6"]
    IL6 -->|"associated with"| C5AR1
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"activates"| C5AR1
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"therapeutic target"| C5AR1
    style C5AR1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

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