DDX5

Understanding Entity Pages

This page aggregates everything SciDEX knows about DDX5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

DDX5 (p68) RNA helicase - structure, function, role in RNA processing, stress granules, Alzheimer's disease, ALS, and Parkinson's disease

View on Wiki →

graph TD
    DDX5["<b>DDX5</b>"]
    MCM8["MCM8"]
    DDX5 -->|"interacts with"| MCM8
    PRP19["PRP19"]
    DDX5 -->|"interacts with"| PRP19
    B_cells["B cells"]
    DDX5 -->|"regulates"| B_cells
    Plasma_cells["Plasma cells"]
    DDX5 -->|"regulates"| Plasma_cells
    CXCL12["CXCL12"]
    DDX5 -->|"regulates"| CXCL12
    CXCR4["CXCR4"]
    DDX5 -->|"regulates"| CXCR4
    Hepatocellular_carcinoma{"Hepatocellular carcinoma"}
    DDX5 -->|"associated with"| Hepatocellular_carcinoma
    Aging{"Aging"}
    DDX5 -->|"regulates"| Aging
    Neurodegeneration{"Neurodegeneration"}
    DDX5 -->|"regulates"| Neurodegeneration
    Als{"Als"}
    DDX5 -->|"regulates"| Als
    Cancer{"Cancer"}
    DDX5 -->|"regulates"| Cancer
    Longevity{"Longevity"}
    DDX5 -->|"regulates"| Longevity
    AGING["AGING"]
    AGING -->|"regulates"| DDX5
    SIRT6["SIRT6"]
    SIRT6 -->|"regulates"| DDX5
    PARP1["PARP1"]
    PARP1 -->|"activates"| DDX5
    NEURODEGENERATION["NEURODEGENERATION"]
    NEURODEGENERATION -->|"regulates"| DDX5
    HNRNPA1["HNRNPA1"]
    HNRNPA1 -->|"activates"| DDX5
    P53["P53"]
    P53 -->|"activates"| DDX5
    MYC["MYC"]
    MYC -->|"regulates"| DDX5
    AGING -->|"associated with"| DDX5
    PSMB9["PSMB9"]
    PSMB9 -->|"associated with"| DDX5
    ENO1["ENO1"]
    ENO1 -->|"associated with"| DDX5
    HNRNPD["HNRNPD"]
    HNRNPD -->|"expressed in"| DDX5
    PI3K["PI3K"]
    PI3K -->|"expressed in"| DDX5
    style DDX5 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0