gene

IL9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about IL9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

75Connections
0Hypotheses
0Analyses
45Outgoing
30Incoming

Summary

IL9 encodes a cytokine of the common gamma chain cytokine family with roles in Th2 immunity, mast cell function, and implications for neuroinflammation.

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🧬 Gene Info
Gene SymbolIL9
Full NameInterleukin 9
Chromosome5q31.1
Protein FamilyCommon gamma chain cytokine family
Molecular Weight~15 kDa
Amino Acids144 aa
Exons5
UniProt IDP15248
NCBI Gene ID3568
Ensembl IDENSG00000145839
OMIM147931
GeneCardsIL9
Human Protein AtlasIL9
Encoded ProteinInterleukin-9 (IL-9)
Protein Length144 amino acids
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsIL4, FGF2, AND, , Fgf
KG Connections75 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: IL9 — AlphaFold P15248 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

IL9 (Interleukin 9)

gene · 2289 words

Genes

index · 271 words

Pathway Diagram

graph TD
    IL9["<b>IL9</b>"]
    Neurodegeneration{"Neurodegeneration"}
    IL9 -->|"biomarker for"| Neurodegeneration
    Als{"Als"}
    IL9 -->|"biomarker for"| Als
    Inflammation{"Inflammation"}
    IL9 -->|"biomarker for"| Inflammation
    Neuroinflammation{"Neuroinflammation"}
    IL9 -->|"biomarker for"| Neuroinflammation
    Alzheimer{"Alzheimer"}
    IL9 -->|"biomarker for"| Alzheimer
    ALS{"ALS"}
    IL9 -->|"biomarker for"| ALS
    VEGFA["VEGFA"]
    IL9 -->|"biomarker for"| VEGFA
    IL4["IL4"]
    IL9 -->|"activates"| IL4
    FGF2["FGF2"]
    IL9 -->|"activates"| FGF2
    GFAP["GFAP"]
    IL9 -->|"biomarker for"| GFAP
    NPTX1["NPTX1"]
    IL9 -->|"biomarker for"| NPTX1
    CHIT1["CHIT1"]
    IL9 -->|"biomarker for"| CHIT1
    SQSTM1["SQSTM1"]
    SQSTM1 -->|"biomarker for"| IL9
    CHIT1 -->|"biomarker for"| IL9
    FGF2 -->|"activates"| IL9
    NEFL["NEFL"]
    NEFL -->|"biomarker for"| IL9
    CHI3L1["CHI3L1"]
    CHI3L1 -->|"biomarker for"| IL9
    MDH1["MDH1"]
    MDH1 -->|"biomarker for"| IL9
    APOE["APOE"]
    APOE -->|"biomarker for"| IL9
    BDNF["BDNF"]
    BDNF -->|"biomarker for"| IL9
    NPTX1 -->|"biomarker for"| IL9
    PDGFRB["PDGFRB"]
    PDGFRB -->|"biomarker for"| IL9
    IL4 -->|"activates"| IL9
    AMYLOID["AMYLOID"]
    AMYLOID -->|"biomarker for"| IL9
    style IL9 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (45)

TargetRelationTypeStr
Amyloid Pathologybiomarker_forprocess0.80
Amyloid Pathologyupregulatesprocess0.80
Neurodegenerationbiomarker_fordisease0.65
Alsbiomarker_fordisease0.65
Inflammationbiomarker_fordisease0.65

Incoming (30)

SourceRelationTypeStr
SQSTM1biomarker_forgene0.60
CHIT1biomarker_forgene0.60
FGF2activatesgene0.60
NEFLbiomarker_forgene0.60
CHI3L1biomarker_forgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found