TRPC6

Understanding Entity Pages

This page aggregates everything SciDEX knows about TRPC6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TRPC6 is a gene implicated in neurodegeneration research. Key relationships include: associated with, therapeutic target, inhibits. Associated with ALS, Als, Cardiovascular. Connected to 36 entities in the SciDEX knowledge graph.

View on Wiki →

graph TD
    TRPC6["<b>TRPC6</b>"]
    calcium_influx["calcium influx"]
    TRPC6 -->|"causes"| calcium_influx
    Als{"Als"}
    TRPC6 -->|"associated with"| Als
    Obesity{"Obesity"}
    TRPC6 -->|"therapeutic target"| Obesity
    Ms{"Ms"}
    TRPC6 -->|"associated with"| Ms
    Diabetes{"Diabetes"}
    TRPC6 -->|"associated with"| Diabetes
    TRPC6 -->|"associated with"| Obesity
    ALS{"ALS"}
    TRPC6 -->|"associated with"| ALS
    HCRTR1["HCRTR1"]
    TRPC6 -->|"therapeutic target"| HCRTR1
    Calcium_Signaling(["Calcium Signaling"])
    TRPC6 -->|"activates"| Calcium_Signaling
    PNOC["PNOC"]
    TRPC6 -->|"associated with"| PNOC
    HCRTR2["HCRTR2"]
    TRPC6 -->|"associated with"| HCRTR2
    neurodegeneration["neurodegeneration"]
    TRPC6 -->|"implicated in"| neurodegeneration
    NFATC1["NFATC1"]
    NFATC1 -->|"activates"| TRPC6
    HCRTR2 -->|"therapeutic target"| TRPC6
    PNOC -->|"therapeutic target"| TRPC6
    GENES["GENES"]
    GENES -->|"therapeutic target"| TRPC6
    HCRTR1 -->|"therapeutic target"| TRPC6
    PIEZO1["PIEZO1"]
    PIEZO1 -->|"activates"| TRPC6
    HCRTR1 -->|"associated with"| TRPC6
    GENES -->|"associated with"| TRPC6
    PNOC -->|"associated with"| TRPC6
    AND["AND"]
    AND -->|"associated with"| TRPC6
    HCRTR2 -->|"associated with"| TRPC6
    style TRPC6 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0