Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ARTHRITIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ARTHRITIS |
Knowledge base pages for this entity
graph TD
ARTHRITIS["ARTHRITIS"]
ARTHRITIS -->|"activates"| Angiogenesis["Angiogenesis"]
ARTHRITIS -->|"regulates"| Oxidative_Stress["Oxidative Stress"]
ARTHRITIS -->|"inhibits"| Ferroptosis["Ferroptosis"]
ARTHRITIS -->|"activates"| Mtor["Mtor"]
FUT8["FUT8"] -->|"activates"| ARTHRITIS
ST6GAL1["ST6GAL1"] -->|"activates"| ARTHRITIS
ANGPT1["ANGPT1"] -->|"activates"| ARTHRITIS
BMP2["BMP2"] -->|"activates"| ARTHRITIS
FGF2["FGF2"] -->|"activates"| ARTHRITIS
PDGFRB["PDGFRB"] -->|"activates"| ARTHRITIS
RUNX2["RUNX2"] -->|"activates"| ARTHRITIS
VEGF["VEGF"] -->|"activates"| ARTHRITIS| Target | Relation | Type | Str |
|---|---|---|---|
| Angiogenesis | activates | pathway | 0.55 |
| Oxidative Stress | regulates | pathway | 0.55 |
| Ferroptosis | inhibits | pathway | 0.55 |
| Ferroptosis | activates | pathway | 0.55 |
| Apoptosis | associated_with | pathway | 0.55 |
| Autophagy | associated_with | pathway | 0.55 |
| Mtor | activates | pathway | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| RLN | associated_with | protein | 0.75 |
| FUT8 | activates | gene | 0.65 |
| ST6GAL1 | activates | gene | 0.65 |
| ANGPT1 | activates | gene | 0.65 |
| BMP2 | activates | gene | 0.65 |
| FGF2 | activates | gene | 0.65 |
| PDGFRB | activates | gene | 0.65 |
| VEGF | activates | gene | 0.65 |
| VEGFB | activates | gene | 0.65 |
| GJA1 | regulates | gene | 0.65 |
| TERT | regulates | gene | 0.65 |
| CD14 | regulates | gene | 0.65 |
| GPX4 | inhibits | gene | 0.65 |
| SLC7A11 | inhibits | gene | 0.65 |
| FER | activates | gene | 0.65 |
| GPX4 | activates | gene | 0.65 |
| MMP1 | inhibits | gene | 0.65 |
| MMP3 | inhibits | gene | 0.65 |
| SLC7A11 | activates | gene | 0.65 |
| SOX9 | inhibits | gene | 0.65 |
| ATF6 | activates | gene | 0.65 |
| EIF2AK3 | activates | gene | 0.65 |
| ERN1 | activates | gene | 0.65 |
| HSPA5 | activates | gene | 0.65 |
| CD8 | associated_with | gene | 0.65 |
| OVERVIEW | associated_with | gene | 0.65 |
| STING | associated_with | gene | 0.65 |
| STING1 | associated_with | gene | 0.65 |
| RUNX2 | activates | gene | 0.65 |
| P53 | inhibits | gene | 0.65 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||