concept

LUTEOLIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LUTEOLIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

67Connections

0Hypotheses

0Analyses

20Outgoing

15Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	LUTEOLIN
Key Genes/Proteins	MMP9, AKT
Related Diseases	INFLAMMATION, OSTEOPOROSIS, BREAST CANCER, METASTASIS, ATHEROSCLEROSIS
Related Pathways	AKT_MTOR_PATHWAY

Wiki Pages (5)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    LUTEOLIN["LUTEOLIN"]
    LUTEOLIN -->|"inhibits"| Triple_Negative_Breast_Cancer["Triple-Negative Breast Cancer"]
    LUTEOLIN -->|"inhibits"| Cell_Proliferation["Cell Proliferation"]
    LUTEOLIN -->|"inhibits"| Cell_Metastasis["Cell Metastasis"]
    LUTEOLIN -->|"downregulates"| MMP9["MMP9"]
    LUTEOLIN -->|"activates"| PI3K_AKT_axis["PI3K/AKT axis"]
    LUTEOLIN -->|"treats"| postmenopausal_osteoporosis["postmenopausal osteoporosis"]
    LUTEOLIN -->|"inhibits"| Akt_Mtor["Akt/Mtor"]
    LUTEOLIN -->|"activates"| PI3K_AKT["PI3K/AKT"]

Outgoing (52)

Target	Relation	Type	Str
MMP9	regulates	protein	0.72
AKT_MTOR_PATHWAY	inhibits	pathway	0.72
INFLAMMATION	treats	phenotype	0.70
INFLAMMATION	activates	phenotype	0.70
OSTEOPOROSIS	treats	disease	0.65
BREAST CANCER	inhibits	disease	0.65
METASTASIS	inhibits	phenotype	0.65
AKT	activates	gene	0.65
AKT	inhibits	gene	0.65
MMP9	inhibits	gene	0.65
ATHEROSCLEROSIS	inhibits	disease	0.65
CELL PROLIFERATION	activates	phenotype	0.65
TNBC	treats	disease	0.64
EMT	inhibits	phenotype	0.64
PI3K	associated_with	gene	0.45
AKT	associated_with	gene	0.45
CANCER	associated_with	disease	0.45
MTOR	associated_with	gene	0.45
MMP9	associated_with	gene	0.45
NRF2	associated_with	gene	0.45

Incoming (15)

Source	Relation	Type	Str
CHOLESTEROL	inhibits	phenotype	0.65
INFLAMMATION	associated_with	phenotype	0.50
FERROPTOSIS	associated_with	phenotype	0.50
APOPTOSIS	associated_with	phenotype	0.50
ATHEROSCLEROSIS	associated_with	disease	0.50
ANGIOGENESIS	associated_with	phenotype	0.50
OSTEOPOROSIS	associated_with	disease	0.45
PYROPTOSIS	associated_with	phenotype	0.45
CELL PROLIFERATION	associated_with	phenotype	0.45
MTOR SIGNALING	associated_with	pathway	0.45
BREAST CANCER	associated_with	disease	0.45
METASTASIS	associated_with	phenotype	0.45
EPITHELIAL-MESENCHYMAL TRANSITION	associated_with	phenotype	0.45
REMYELINATION	associated_with	phenotype	0.45
CHOLESTEROL	associated_with	phenotype	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

LUTEOLIN

Understanding Entity Pages

Wiki Pages (5)

adam9

aim2-inflammasome-modulator-therapy

Autophagy Modulation with Bioactive Compounds for Neurodegeneration