CDK12

Understanding Entity Pages

This page aggregates everything SciDEX knows about CDK12: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CDK12 is a protein involved in neurodegeneration research. Key relationships include: activates, inhibits, therapeutic target. Associated with Cancer, Ms, Tumor. Connected to 25 entities in the SciDEX knowledge graph.

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graph TD
    CDK12["<b>CDK12</b>"]
    Cancer{"Cancer"}
    CDK12 -->|"activates"| Cancer
    Ms{"Ms"}
    CDK12 -->|"inhibits"| Ms
    Tumor{"Tumor"}
    CDK12 -->|"therapeutic target"| Tumor
    CDK12 -->|"inhibits"| Cancer
    ATG3["ATG3"]
    CDK12 -->|"activates"| ATG3
    CANCER["CANCER"]
    CDK12 -->|"activates"| CANCER
    ATG7["ATG7"]
    CDK12 -->|"activates"| ATG7
    AUTOPHAGY["AUTOPHAGY"]
    CDK12 -->|"activates"| AUTOPHAGY
    CDK4["CDK4"]
    CDK12 -->|"activates"| CDK4
    ATG16L1["ATG16L1"]
    CDK12 -->|"activates"| ATG16L1
    LC3["LC3"]
    CDK12 -->|"activates"| LC3
    Epigenetic(["Epigenetic"])
    CDK12 -->|"activates"| Epigenetic
    ATG9A["ATG9A"]
    ATG9A -->|"activates"| CDK12
    ARAF["ARAF"]
    ARAF -->|"activates"| CDK12
    BECLIN1["BECLIN1"]
    BECLIN1 -->|"activates"| CDK12
    ATG12["ATG12"]
    ATG12 -->|"activates"| CDK12
    MYC["MYC"]
    MYC -->|"activates"| CDK12
    GENES["GENES"]
    GENES -->|"inhibits"| CDK12
    ENDOGENOUS_DNA["ENDOGENOUS DNA"]
    ENDOGENOUS_DNA -->|"expressed in"| CDK12
    MYC -->|"inhibits"| CDK12
    CANCER -->|"inhibits"| CDK12
    style CDK12 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0