IGF2BP2

Understanding Entity Pages

This page aggregates everything SciDEX knows about IGF2BP2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Gene profile: IGF2BP2 - Insulin-like Growth Factor 2 mRNA-Binding Protein 2 involved in RNA localization, translation regulation, stress granule dynamics, synaptic function, and neurodegeneration

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graph TD
    IGF2BP2["<b>IGF2BP2</b>"]
    Carcinoma{"Carcinoma"}
    IGF2BP2 -->|"inhibits"| Carcinoma
    Cancer{"Cancer"}
    IGF2BP2 -->|"regulates"| Cancer
    Tumor{"Tumor"}
    IGF2BP2 -->|"activates"| Tumor
    Ms{"Ms"}
    IGF2BP2 -->|"activates"| Ms
    IGF2BP2 -->|"activates"| Cancer
    IGF2BP2 -->|"activates"| Carcinoma
    IGF2BP2 -->|"therapeutic target"| Ms
    LC3["LC3"]
    IGF2BP2 -->|"regulates"| LC3
    Epigenetic(["Epigenetic"])
    IGF2BP2 -->|"inhibits"| Epigenetic
    Autophagy(["Autophagy"])
    IGF2BP2 -->|"inhibits"| Autophagy
    PRKN["PRKN"]
    IGF2BP2 -->|"activates"| PRKN
    METTL3["METTL3"]
    IGF2BP2 -->|"activates"| METTL3
    CANCER["CANCER"]
    CANCER -->|"regulates"| IGF2BP2
    AUTOPHAGY["AUTOPHAGY"]
    AUTOPHAGY -->|"inhibits"| IGF2BP2
    CANCER -->|"activates"| IGF2BP2
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"activates"| IGF2BP2
    HNRNPU["HNRNPU"]
    HNRNPU -->|"interacts with"| IGF2BP2
    MYC["MYC"]
    MYC -->|"activates"| IGF2BP2
    CSF1["CSF1"]
    CSF1 -->|"activates"| IGF2BP2
    CTCF["CTCF"]
    CTCF -->|"activates"| IGF2BP2
    EP300["EP300"]
    EP300 -->|"interacts with"| IGF2BP2
    style IGF2BP2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0