CTCF

Understanding Entity Pages

This page aggregates everything SciDEX knows about CTCF: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CTCF is a protein involved in neurodegeneration research. Key relationships include: associated with, regulates, activates. Associated with Aging, Als, Anxiety. Connected to 62 entities in the SciDEX knowledge graph.

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graph TD
    CTCF["<b>CTCF</b>"]
    Ms{"Ms"}
    CTCF -->|"regulates"| Ms
    Cancer{"Cancer"}
    CTCF -->|"regulates"| Cancer
    Tumor{"Tumor"}
    CTCF -->|"regulates"| Tumor
    Als{"Als"}
    CTCF -->|"regulates"| Als
    Aging{"Aging"}
    CTCF -->|"regulates"| Aging
    Carcinoma{"Carcinoma"}
    CTCF -->|"activates"| Carcinoma
    CTCF -->|"therapeutic target"| Ms
    CTCF -->|"activates"| Cancer
    CTCF -->|"activates"| Tumor
    KLF2["KLF2"]
    CTCF -->|"regulates"| KLF2
    PARP1["PARP1"]
    CTCF -->|"activates"| PARP1
    Inflammasome(["Inflammasome"])
    CTCF -->|"regulates"| Inflammasome
    P53["P53"]
    P53 -->|"regulates"| CTCF
    CANCER["CANCER"]
    CANCER -->|"regulates"| CTCF
    PARP1 -->|"activates"| CTCF
    KLF2 -->|"regulates"| CTCF
    BNIP3L["BNIP3L"]
    BNIP3L -->|"interacts with"| CTCF
    HNRNPU["HNRNPU"]
    HNRNPU -->|"interacts with"| CTCF
    MYC["MYC"]
    MYC -->|"activates"| CTCF
    CSF1["CSF1"]
    CSF1 -->|"therapeutic target"| CTCF
    CANCER -->|"activates"| CTCF
    style CTCF fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0