concept

OSTEOBLAST

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about OSTEOBLAST: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

69Connections

0Hypotheses

0Analyses

0Outgoing

50Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	OSTEOBLAST

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    OSTEOBLAST["OSTEOBLAST"]
    EPHB4["EPHB4"] -->|"activates"| OSTEOBLAST
    COMPLEMENT["COMPLEMENT"] -->|"activates"| OSTEOBLAST
    RHOA["RHOA"] -->|"activates"| OSTEOBLAST
    VEGF["VEGF"] -->|"activates"| OSTEOBLAST
    VEGFB["VEGFB"] -->|"activates"| OSTEOBLAST
    ANGPT1["ANGPT1"] -->|"activates"| OSTEOBLAST
    PDGFRB["PDGFRB"] -->|"activates"| OSTEOBLAST
    FGF2["FGF2"] -->|"activates"| OSTEOBLAST

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (69)

Source	Relation	Type	Str
OSTEOCALCIN	expressed_in	biomarker	0.85
OCN	biomarker_for	protein	0.80
RHOA	involved_in	gene	0.75
EPHB4	activates	gene	0.60
RHOA	activates	gene	0.60
VEGF	activates	gene	0.60
VEGFB	activates	gene	0.60
ANGPT1	activates	gene	0.60
PDGFRB	activates	gene	0.60
FGF2	activates	gene	0.60
BMP2	activates	gene	0.60
ATF4	regulates	gene	0.60
RANKL	interacts_with	gene	0.60
RANK	interacts_with	gene	0.60
PDGFRB	expressed_in	gene	0.60
SIRT1	activates	gene	0.60
MTOR	activates	gene	0.60
PI3K	activates	gene	0.60
SOX9	activates	gene	0.60
NLRP3	activates	gene	0.60
C1QA	activates	gene	0.60
CCL20	activates	gene	0.60
LRP1	activates	gene	0.60
AKT	expressed_in	gene	0.60
STAT3	expressed_in	gene	0.60
JAG1	activates	gene	0.60
BMP2	therapeutic_target	gene	0.60
COMPLEMENT	activates	gene	0.60
RUNX2	activates	gene	0.60
WNT	regulates	gene	0.60
CYTOKINES	regulates	gene	0.60
RUNX2	regulates	gene	0.60
PDGF	expressed_in	gene	0.60
RNA	expressed_in	gene	0.60
AMPK	activates	gene	0.60
BMP	activates	gene	0.60
NF-KB	activates	gene	0.60
APOPTOSIS	therapeutic_target	gene	0.60
MITOPHAGY	therapeutic_target	gene	0.60
MITOCHONDRIA	therapeutic_target	gene	0.60
PYROPTOSIS	activates	gene	0.60
MITOCHONDRIA	activates	gene	0.60
RNA	activates	gene	0.60
CYTOKINES	activates	gene	0.60
ATP6AP2	regulates	gene	0.60
EXERCISE	expressed_in	gene	0.60
NOTCH	expressed_in	gene	0.60
NOTCH	activates	gene	0.60
Aging	expressed_in	disease	0.55
Als	activates	disease	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

OSTEOBLAST

Understanding Entity Pages

Wiki Pages (20)

FGF23 — Fibroblast Growth Factor 23

Gamma-Synuclein Protein

EPHA5 Gene

gaucher-disease-pathway

FLT1 Gene

IL11 Gene

WNT10A Gene

DKK1 — Dickkopf WNT Signaling Pathway Inhibitor 1

FOXO1 Gene

GALNT3 — Polypeptide N-acetylgalactosaminyltransferase 3

GPR132 Gene

ERK2 Protein

HDAC4 Protein

TMEM119 — Transmembrane Protein 119

DDX5 Gene

TGFBI

GPNMB (Glycoprotein NMB)

CD44 - Cell Surface Glycoprotein