PON1

Understanding Entity Pages

This page aggregates everything SciDEX knows about PON1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PON1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, therapeutic target, causes. Associated with Als, Atherosclerosis, Breast Cancer. Connected to 31 entities in the SciDEX knowledge graph.

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graph TD
    PON1["<b>PON1</b>"]
    Carcinoma{"Carcinoma"}
    PON1 -->|"therapeutic target"| Carcinoma
    Als{"Als"}
    PON1 -->|"therapeutic target"| Als
    Ms{"Ms"}
    PON1 -->|"therapeutic target"| Ms
    Tumor{"Tumor"}
    PON1 -->|"therapeutic target"| Tumor
    IGF1["IGF1"]
    PON1 -->|"therapeutic target"| IGF1
    PER["PER"]
    PON1 -->|"therapeutic target"| PER
    SERPINE1["SERPINE1"]
    PON1 -->|"therapeutic target"| SERPINE1
    APOA1["APOA1"]
    PON1 -->|"therapeutic target"| APOA1
    PPARGC1A["PPARGC1A"]
    PON1 -->|"therapeutic target"| PPARGC1A
    ESR1["ESR1"]
    PON1 -->|"therapeutic target"| ESR1
    neurodegeneration["neurodegeneration"]
    PON1 -->|"implicated in"| neurodegeneration
    style PON1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0