SHANK3

Understanding Entity Pages

This page aggregates everything SciDEX knows about SHANK3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for SHANK3 - SH3 and Multiple Ankyrin Repeat Domains 3

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graph TD
    SHANK3["<b>SHANK3</b>"]
    Als{"Als"}
    SHANK3 -->|"associated with"| Als
    Autism{"Autism"}
    SHANK3 -->|"contributes to"| Autism
    Ms{"Ms"}
    SHANK3 -->|"contributes to"| Ms
    SHANK3 -->|"interacts with"| Ms
    SHANK3 -->|"inhibits"| Autism
    Autophagy(["Autophagy"])
    SHANK3 -->|"associated with"| Autophagy
    Synaptic_Plasticity(["Synaptic Plasticity"])
    SHANK3 -->|"interacts with"| Synaptic_Plasticity
    Mtor(["Mtor"])
    SHANK3 -->|"inhibits"| Mtor
    AUTOPHAGY["AUTOPHAGY"]
    SHANK3 -->|"associated with"| AUTOPHAGY
    neurodegeneration["neurodegeneration"]
    SHANK3 -->|"implicated in"| neurodegeneration
    MTOR["MTOR"]
    MTOR -->|"inhibits"| SHANK3
    style SHANK3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0