WNT7A

Understanding Entity Pages

This page aggregates everything SciDEX knows about WNT7A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

WNT7A (Wnt Family Member 7A) is a secreted signaling molecule that activates canonical and non-canonical Wnt pathways, playing critical roles in axonal remodeling, synapse formation, and dopaminergic neuron development.

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graph TD
    WNT7A["<b>WNT7A</b>"]
    Carcinoma{"Carcinoma"}
    WNT7A -->|"inhibits"| Carcinoma
    Ms{"Ms"}
    WNT7A -->|"inhibits"| Ms
    Cancer{"Cancer"}
    WNT7A -->|"inhibits"| Cancer
    Tumor{"Tumor"}
    WNT7A -->|"inhibits"| Tumor
    LZTS1["LZTS1"]
    WNT7A -->|"associated with"| LZTS1
    DCC["DCC"]
    WNT7A -->|"associated with"| DCC
    KCNK2["KCNK2"]
    WNT7A -->|"inhibits"| KCNK2
    CD44["CD44"]
    WNT7A -->|"inhibits"| CD44
    FGF10["FGF10"]
    WNT7A -->|"inhibits"| FGF10
    DLC1["DLC1"]
    WNT7A -->|"associated with"| DLC1
    KCNH1["KCNH1"]
    WNT7A -->|"inhibits"| KCNH1
    NCAM1["NCAM1"]
    WNT7A -->|"inhibits"| NCAM1
    CDKN2A["CDKN2A"]
    CDKN2A -->|"associated with"| WNT7A
    TLR4["TLR4"]
    TLR4 -->|"inhibits"| WNT7A
    CANCER["CANCER"]
    CANCER -->|"inhibits"| WNT7A
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"inhibits"| WNT7A
    TNC["TNC"]
    TNC -->|"inhibits"| WNT7A
    NTRK2["NTRK2"]
    NTRK2 -->|"inhibits"| WNT7A
    PAK1["PAK1"]
    PAK1 -->|"inhibits"| WNT7A
    style WNT7A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0