gene

apoc2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about apoc2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

128Connections

0Hypotheses

0Analyses

7Outgoing

5Incoming

No summary available yet. View on Wiki →

🧬 Gene Info

Gene Symbol	APOC2
Chromosome	19q13.32
Function	LPL Activation: APOC2 is the essential cofactor for lipoprotein lipase
Primary Expression	the liver and small intestine
Molecular Weight	8.8 kDa
Amino Acids	79 aa
Exons	4
Pathways	Cholesterol
Ensembl ID	ENSG00000134901
GeneCards	APOC2
Human Protein Atlas	APOC2
Associated Diseases	Dementia, Aging, Alzheimer, Als, Ms, hypertriglyceridemia
Interactions	apoc3, LRP1, CYP46A1, LDLR, LRP8, APOE
KG Connections	12 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (9)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    APOC2["APOC2"]
    APOC2 -->|"regulates"| HNF4A["HNF4A"]
    APOC2 -->|"regulates"| PPARA["PPARA"]
    APOC2 -->|"regulates"| LDLR["LDLR"]
    APOC2 -->|"causes"| hypertriglyceridemia["hypertriglyceridemia"]
    APOC2 -->|"activates"| JAK_STAT_signaling_pathway["JAK-STAT signaling pathway"]
    APOC2 -.biomarker for.-> Carcinoma["Carcinoma"]
    APOC2 -.biomarker for.-> Tumor["Tumor"]
    APOC2 -->|"regulates"| Alzheimer["Alzheimer"]
    CH25H["CH25H"] -->|"activates"| APOC2
    LRP8["LRP8"] -->|"activates"| APOC2
    APOA1["APOA1"] -->|"activates"| APOC2
    MAPT["MAPT"] -->|"regulates"| APOC2
    LRP1["LRP1"] -->|"activates"| APOC2
    LIPA["LIPA"] -->|"regulates"| APOC2
    ALZHEIMER["ALZHEIMER"] -->|"regulates"| APOC2
    APP["APP"] -->|"regulates"| APOC2

Outgoing (59)

Target	Relation	Type	Str
apoc3	activates	gene	0.50
LRP1	activates	gene	0.50
CYP46A1	activates	gene	0.50
LDLR	activates	gene	0.50
LRP8	activates	gene	0.50
Cholesterol	activates	pathway	0.50
SOAT1	activates	concept	0.50

Incoming (69)

Source	Relation	Type	Str
APOE	activates	gene	0.50
ABCA1	activates	gene	0.50
abca2	activates	gene	0.50
APOA1	activates	gene	0.50
apoc1	activates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

apoc2

Understanding Entity Pages

Wiki Pages (9)

APOC4 — Apolipoprotein C-IV

APOC1 Gene — Apolipoprotein C-I

Apolipoprotein C-III Protein

Apolipoprotein C-II Protein

APOC2 Gene

APOC2 Protein

LZTS1 — Leucine Zipper Tumor Suppressor 1