EHMT2

Understanding Entity Pages

This page aggregates everything SciDEX knows about EHMT2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

EHMT2 — Euchromatic Histone Lysine Methyltransferase 2

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graph TD
    EHMT2["<b>EHMT2</b>"]
    Cancer{"Cancer"}
    EHMT2 -->|"inhibits"| Cancer
    Als{"Als"}
    EHMT2 -->|"inhibits"| Als
    Aging{"Aging"}
    EHMT2 -->|"inhibits"| Aging
    Lymphoma{"Lymphoma"}
    EHMT2 -->|"associated with"| Lymphoma
    Ms{"Ms"}
    EHMT2 -->|"inhibits"| Ms
    Heart_Failure{"Heart Failure"}
    EHMT2 -->|"inhibits"| Heart_Failure
    EHMT2 -->|"activates"| Aging
    EHMT2 -->|"activates"| Als
    EHMT2 -->|"activates"| Cancer
    EHMT2 -->|"activates"| Heart_Failure
    EHMT2 -->|"therapeutic target"| Aging
    EHMT2 -->|"therapeutic target"| Ms
    BAX["BAX"]
    BAX -->|"associated with"| EHMT2
    FOXO1["FOXO1"]
    FOXO1 -->|"associated with"| EHMT2
    JUN["JUN"]
    JUN -->|"inhibits"| EHMT2
    BCL_2["BCL-2"]
    BCL_2 -->|"associated with"| EHMT2
    BCL2["BCL2"]
    BCL2 -->|"associated with"| EHMT2
    KDM1A["KDM1A"]
    KDM1A -->|"therapeutic target"| EHMT2
    HDAC2["HDAC2"]
    HDAC2 -->|"therapeutic target"| EHMT2
    DNMT1["DNMT1"]
    DNMT1 -->|"therapeutic target"| EHMT2
    AND["AND"]
    AND -->|"associated with"| EHMT2
    CASPASE8["CASPASE8"]
    CASPASE8 -->|"associated with"| EHMT2
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"inhibits"| EHMT2
    style EHMT2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0