concept

MIR454

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIR454: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

92Connections
0Hypotheses
0Analyses
47Outgoing
45Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameMIR454
Key Genes/ProteinsFAM83A, TSPAN1, MAP1LC3, ATG, AMPK, MTOR
Related DiseasesTumor, Cancer, ALS, Carcinoma, Als
Related PathwaysAutophagy, Wnt, Mtor

Pathway Diagram

graph TD
    MIR454["MIR454"]
    MIR454 -->|"regulates"| FAM83A["FAM83A"]
    MIR454 -->|"regulates"| TSPAN1["TSPAN1"]
    MIR454 -->|"activates"| Tumor["Tumor"]
    MIR454 -->|"activates"| Cancer["Cancer"]
    MIR454 -->|"activates"| ALS["ALS"]
    MIR454 -->|"activates"| Als["Als"]
    MIR454 -->|"activates"| Autophagy["Autophagy"]
    MIR454 -->|"activates"| Wnt["Wnt"]
    WNT["WNT"] -->|"activates"| MIR454
    CTNNB1["CTNNB1"] -->|"activates"| MIR454
    AUTOPHAGY["AUTOPHAGY"] -->|"activates"| MIR454
    FAM83A -->|"activates"| MIR454
    AND["AND"] -->|"activates"| MIR454
    P62["P62"] -->|"activates"| MIR454
    CANCER["CANCER"] -->|"activates"| MIR454
    TSPAN1 -->|"activates"| MIR454

Outgoing (47)

TargetRelationTypeStr
FAM83Aregulatesgene0.85
TSPAN1regulatesgene0.85
Tumoractivatesdisease0.65
Canceractivatesdisease0.65
ALSactivatesdisease0.65

Incoming (45)

SourceRelationTypeStr
LAMP1associated_withgene0.60
LC3associated_withgene0.60
RAB7Aassociated_withgene0.60
WNTactivatesgene0.60
RASassociated_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found