concept

CSNK1A1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CSNK1A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

166Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

Summary

CSNK1A1 is a concept in neurodegeneration research. Key relationships include: associated with, activates, regulates. Associated with ALS, Als, Autoimmune. Connected to 79 entities in the SciDEX knowledge graph.

View on Wiki →

💡 Concept Info

Name	CSNK1A1
Key Genes/Proteins	STING1
Related Diseases	Autoimmunity, Carcinoma, Cancer, Als, Tumor
Related Pathways	autophagy pathway

Wiki Pages (2)

Knowledge base pages for this entity

SMO — Smoothened, Frizzled Class Receptor

gene · 1600 words

→

STING1 Gene

gene · 977 words

→

Pathway Diagram

graph TD
    CSNK1A1["CSNK1A1"]
    CSNK1A1 -->|"inhibits"| STING1["STING1"]
    CSNK1A1 -->|"activates"| Als["Als"]
    CSNK1A1 -->|"activates"| Tumor["Tumor"]
    CSNK1A1 -->|"activates"| Autoimmune["Autoimmune"]
    CSNK1A1 -->|"activates"| Carcinoma["Carcinoma"]
    CSNK1A1 -->|"activates"| ALS["ALS"]
    CSNK1A1 -->|"activates"| SQSTM1["SQSTM1"]
    SSTC3["SSTC3"] -->|"activates"| CSNK1A1
    P62["P62"] -->|"activates"| CSNK1A1
    SQSTM1 -->|"activates"| CSNK1A1
    CGAS["CGAS"] -->|"activates"| CSNK1A1
    GENES["GENES"] -->|"activates"| CSNK1A1
    PIK3C3["PIK3C3"] -->|"activates"| CSNK1A1
    RUBCN["RUBCN"] -->|"activates"| CSNK1A1
    SMURF1["SMURF1"] -->|"regulates"| CSNK1A1
    UVRAG["UVRAG"] -->|"regulates"| CSNK1A1
    STING1 -->|"activates"| CSNK1A1

Outgoing (98)

Target	Relation	Type	Str
ds-83b31ef18d49	provides_data_for	dataset	1.00
SQSTM1	phosphorylates	entity	0.90
Autophagic Degradation	associated_with	process	0.90
STING	interacts_with	entity	0.85
STING1	phosphorylates	protein	0.85
Autoimmunity	protects_against	disease	0.85
STING1	inhibits	gene	0.72
autophagy pathway	participates_in	pathway	0.70
Carcinoma	associated_with	disease	0.65
Cancer	associated_with	disease	0.65
Als	activates	disease	0.65
Tumor	activates	disease	0.65
Autoimmune	activates	disease	0.65
Carcinoma	activates	disease	0.65
Als	regulates	disease	0.65
Tumor	regulates	disease	0.65
ALS	activates	disease	0.65
Hepatocellular Carcinoma	activates	disease	0.65
Cancer	regulates	disease	0.65
Alzheimer	regulates	disease	0.65
Glioblastoma	regulates	disease	0.65
Ms	regulates	disease	0.65
STING1	interacts_with	gene	0.64
SQSTM1	activates	gene	0.64
GAPDH	associated_with	gene	0.60
GSK3B	associated_with	gene	0.60
APC	associated_with	gene	0.60
CTNNB1	associated_with	gene	0.60
LAMP1	associated_with	gene	0.60
MYC	associated_with	gene	0.60
RAB7A	associated_with	gene	0.60
AMPK	associated_with	gene	0.60
TCF4	associated_with	gene	0.60
LC3	associated_with	gene	0.60
BECN1	associated_with	gene	0.60
Mtor	associated_with	pathway	0.60
Autophagy	associated_with	pathway	0.60
Wnt	associated_with	pathway	0.60
STING1	activates	gene	0.60
Innate Immunity	activates	pathway	0.60
UVRAG	regulates	gene	0.60
BECN1	activates	gene	0.60
Mtor	activates	pathway	0.60
Autophagy	activates	pathway	0.60
P62	activates	gene	0.60
RUBCN	activates	gene	0.60
GFP	associated_with	gene	0.60
AUTOPHAGY	associated_with	gene	0.60
MAP1LC3	associated_with	gene	0.60
AXIN2	associated_with	gene	0.60

Incoming (68)

Source	Relation	Type	Str
ds-83b31ef18d49	data_in	dataset	1.00
P62	activates	gene	0.70
SSTC3	activates	drug	0.64
SQSTM1	associated_with	gene	0.60
MAP1LC3	associated_with	gene	0.60
AXIN2	associated_with	gene	0.60
ATG	associated_with	gene	0.60
MTOR	associated_with	gene	0.60
SQSTM1	activates	gene	0.60
CGAS	activates	gene	0.60
GENES	activates	gene	0.60
PIK3C3	activates	gene	0.60
RUBCN	activates	gene	0.60
SMURF1	regulates	gene	0.60
AMPK	associated_with	gene	0.60
UVRAG	regulates	gene	0.60
STING1	activates	gene	0.60
MYC	associated_with	gene	0.60
LC3	associated_with	gene	0.60
CANCER	associated_with	gene	0.60
IFN	regulates	gene	0.60
RAS	associated_with	gene	0.60
RAB7A	associated_with	gene	0.60
TCF4	associated_with	gene	0.60
AUTOPHAGY	associated_with	gene	0.60
AXIN	associated_with	gene	0.60
GAPDH	associated_with	gene	0.60
APC	associated_with	gene	0.60
LAMP1	associated_with	gene	0.60
CTNNB1	associated_with	gene	0.60
GFP	associated_with	gene	0.60
BECN1	associated_with	gene	0.60
GSK3B	associated_with	gene	0.60
MTORC1	activates	gene	0.60
BECN1	activates	gene	0.60
AUTOPHAGY	activates	gene	0.60
AND	regulates	gene	0.60
AND	activates	gene	0.60
GLIOBLASTOMA	regulates	gene	0.60
AMYLOID	regulates	gene	0.60
CANCER	regulates	gene	0.60
ALZHEIMER	regulates	gene	0.60
FURIN	regulates	gene	0.60
GENES	regulates	gene	0.60
BACE1	regulates	gene	0.60
MICROGLIA	regulates	gene	0.60
GBM	regulates	gene	0.60
ALZHEIMER'S DISEASE	regulates	gene	0.60
WNT	associated_with	gene	0.60
APC	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found