NEPRILYSIN

Understanding Entity Pages

This page aggregates everything SciDEX knows about NEPRILYSIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

NEPRILYSIN is a protein involved in neurodegeneration research. Key relationships include: activates, associated with, implicated in. Associated with ALS, Alzheimer. Connected to 12 entities in the SciDEX knowledge graph.

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graph TD
    NEPRILYSIN["<b>NEPRILYSIN</b>"]
    ALS{"ALS"}
    NEPRILYSIN -->|"activates"| ALS
    Alzheimer{"Alzheimer"}
    NEPRILYSIN -->|"activates"| Alzheimer
    ALZHEIMER["ALZHEIMER"]
    NEPRILYSIN -->|"activates"| ALZHEIMER
    APP["APP"]
    NEPRILYSIN -->|"activates"| APP
    Amyloid(["Amyloid"])
    NEPRILYSIN -->|"associated with"| Amyloid
    neurodegeneration["neurodegeneration"]
    NEPRILYSIN -->|"implicated in"| neurodegeneration
    AMYLOID["AMYLOID"]
    AMYLOID -->|"associated with"| NEPRILYSIN
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"activates"| NEPRILYSIN
    APP_PS1["APP/PS1"]
    APP_PS1 -->|"activates"| NEPRILYSIN
    AHR["AHR"]
    AHR -->|"activates"| NEPRILYSIN
    ALZHEIMER -->|"activates"| NEPRILYSIN
    APP -->|"activates"| NEPRILYSIN
    AND["AND"]
    AND -->|"activates"| NEPRILYSIN
    style NEPRILYSIN fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0