FIS1

Understanding Entity Pages

This page aggregates everything SciDEX knows about FIS1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

FIS1 is a protein involved in neurodegeneration research. Key relationships include: associated with, activates, regulates. Associated with Aging, Als, Alzheimer. Connected to 232 entities in the SciDEX knowledge graph.

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graph TD
    FIS1["FIS1"]
    FIS1 -->|"regulates"| Neuroinflammation["Neuroinflammation"]
    FIS1 -->|"regulates"| Neurodegeneration["Neurodegeneration"]
    FIS1 -->|"regulates"| Inflammation["Inflammation"]
    FIS1 -->|"regulates"| Glioblastoma["Glioblastoma"]
    FIS1 -->|"interacts"| Dementia["Dementia"]
    FIS1 -->|"interacts"| Als["Als"]
    FIS1 -->|"interacts"| Ms["Ms"]
    MFF["MFF"] -->|"activates"| FIS1
    DNM1L["DNM1L"] -->|"target for"| FIS1
    LC3B["LC3B"] -->|"interacts"| FIS1
    MICROGLIA["MICROGLIA"] -->|"interacts"| FIS1
    MFN2["MFN2"] -->|"activates"| FIS1
    CCR5["CCR5"] -->|"interacts"| FIS1
    APP["APP"] -->|"interacts"| FIS1
    DRP1["DRP1"] -->|"regulates"| FIS1
    MFN1["MFN1"] -->|"regulates"| FIS1