Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about VENTRAL TEGMENTAL AREA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | VENTRAL TEGMENTAL AREA |
| Summary | Page for Ventral Tegmental Area |
| Key Genes/Proteins | TH, SIRT1, BDNF |
| Related Diseases | DOPAMINE, PARKINSON'S DISEASE |
Knowledge base pages for this entity
graph TD
VENTRAL_TEGMENTAL_AREA["VENTRAL TEGMENTAL AREA"]
DOPAMINERGIC_NEURONS["DOPAMINERGIC NEURONS"] -->|"activates"| VENTRAL_TEGMENTAL_AREA
AADC["AADC"] -->|"expressed in"| VENTRAL_TEGMENTAL_AREA
SST["SST"] -->|"expressed in"| VENTRAL_TEGMENTAL_AREA
AND["AND"] -->|"expressed in"| VENTRAL_TEGMENTAL_AREA
NEURON["NEURON"] -->|"expressed in"| VENTRAL_TEGMENTAL_AREA
TAAR1["TAAR1"] -->|"expressed in"| VENTRAL_TEGMENTAL_AREA
PER["PER"] -->|"expressed in"| VENTRAL_TEGMENTAL_AREA| Target | Relation | Type | Str |
|---|---|---|---|
| CURCUMIN | associated_with | drug | 0.50 |
| TH | associated_with | gene | 0.50 |
| INTERNEURONS | associated_with | cell_type | 0.50 |
| NEURONS | associated_with | cell_type | 0.45 |
| NEURON | associated_with | cell_type | 0.45 |
| SIRT1 | associated_with | gene | 0.45 |
| DOPAMINE | associated_with | phenotype | 0.45 |
| PARKINSON'S DISEASE | associated_with | disease | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| DOPAMINERGIC NEURONS | activates | cell_type | 0.65 |
| SUBSTANTIA NIGRA | activates | brain_region | 0.50 |
| PREFRONTAL CORTEX | activates | brain_region | 0.35 |
| SIRT1 | implicated_in | gene | 0.35 |
| MICROGLIA | activates | cell_type | 0.35 |
| BDNF | activates | gene | 0.35 |
| NEURON | activates | cell_type | 0.35 |
| NEURON | expressed_in | cell_type | 0.35 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||