BIRC5

Understanding Entity Pages

This page aggregates everything SciDEX knows about BIRC5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

BIRC5 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, associated with, implicated in. Associated with Als, Cancer, Carcinoma. Connected to 48 entities in the SciDEX knowledge graph.

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graph TD
    BIRC5["<b>BIRC5</b>"]
    Als{"Als"}
    BIRC5 -->|"therapeutic target"| Als
    Cancer{"Cancer"}
    BIRC5 -->|"therapeutic target"| Cancer
    Tumor{"Tumor"}
    BIRC5 -->|"therapeutic target"| Tumor
    Ms{"Ms"}
    BIRC5 -->|"associated with"| Ms
    Carcinoma{"Carcinoma"}
    BIRC5 -->|"associated with"| Carcinoma
    CANCER["CANCER"]
    BIRC5 -->|"therapeutic target"| CANCER
    MDM2["MDM2"]
    BIRC5 -->|"therapeutic target"| MDM2
    Akt(["Akt"])
    BIRC5 -->|"therapeutic target"| Akt
    Mtor(["Mtor"])
    BIRC5 -->|"therapeutic target"| Mtor
    Epigenetic(["Epigenetic"])
    BIRC5 -->|"therapeutic target"| Epigenetic
    Mapk(["Mapk"])
    BIRC5 -->|"therapeutic target"| Mapk
    Pi3K(["Pi3K"])
    BIRC5 -->|"therapeutic target"| Pi3K
    MTOR["MTOR"]
    MTOR -->|"therapeutic target"| BIRC5
    PHOX2B["PHOX2B"]
    PHOX2B -->|"therapeutic target"| BIRC5
    PI3K["PI3K"]
    PI3K -->|"therapeutic target"| BIRC5
    AKT["AKT"]
    AKT -->|"therapeutic target"| BIRC5
    IL6["IL6"]
    IL6 -->|"therapeutic target"| BIRC5
    PER["PER"]
    PER -->|"associated with"| BIRC5
    MYC["MYC"]
    MYC -->|"therapeutic target"| BIRC5
    style BIRC5 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0