SciDEX — STAU1

graph TD
    STAU1["STAU1"]
    style STAU1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    STAU1 -->|"interacts"| MTOR([MTOR])
    STAU1 -.->|"inhibits"| Autophagy["Autophagy"]
    STAU1 -.->|"biomarker for"| Spinocerebellar_Ataxia_Type_2["Spinocerebellar Ataxia Type 2"]
    STAU1 -.->|"biomarker for"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    STAU1 -.->|"biomarker for"| Frontotemporal_Degeneration["Frontotemporal Degeneration"]
    STAU1 -.->|"biomarker for"| Huntington_s_Disease["Huntington's Disease"]
    STAU1 -.->|"biomarker for"| Alzheimer_s_Disease["Alzheimer's Disease"]
    STAU1 -.->|"biomarker for"| Parkinson_s_Disease["Parkinson's Disease"]
    ALS([ALS]) -.->|"protects against"| STAU1
    APOPTOSIS([APOPTOSIS]) -.->|"inhibits"| STAU1
    AND([AND]) -.->|"inhibits"| STAU1
    NEURODEGENERATION([NEURODEGENERATION]) -->|"target for"| STAU1
    C9ORF72([C9ORF72]) -->|"activates"| STAU1

Outgoing (111)

Target	Relation	Type	Str
MTOR	interacts_with	gene	0.95
MTOR	upregulates	gene	0.95
Spinocerebellar Ataxia Type 2	associated_with	disease	0.91
MTOR	regulates	gene	0.90
MTOR	activates	gene	0.90
Autophagy	inhibits	process	0.90
P53	activates	gene	0.90
apoptosis	promotes	process	0.90
neurodegeneration	promotes	process	0.90
mTOR Translation	associated_with	process	0.90
Alzheimer'S Disease	associated_with	disease	0.88
Parkinson'S Disease	associated_with	disease	0.88
MTOR	binds	protein	0.88
Stress Granule Formation	involved_in	process	0.85
Neurodegeneration	contributes_to	process	0.85
P53	interacts_with	gene	0.85
Neurodegeneration	targets	process	0.85
Autophagy-Lysosome Function	inhibits	pathway	0.85
mTOR	interacts_with	gene	0.80
mTOR	regulates	gene	0.80
neurodegeneration	implicated_in	disease	0.80
KIF5	interacts_with	protein	0.80
RNA Metabolism	mediates	process	0.80
oxidative stress response	participates_in	pathway	0.70
MTOR	promotes	protein	0.70
mTOR signaling	activates	pathway	0.70
neurodegenerative diseases	associated_with	disease	0.70
Neurodegeneration	therapeutic_target	disease	0.65
Als	protects_against	disease	0.65
Ms	therapeutic_target	disease	0.65
Amyotrophic Lateral Sclerosis	associated_with	disease	0.65
Dementia	associated_with	disease	0.65
Ataxia	associated_with	disease	0.65
Tumor	associated_with	disease	0.65
Huntington	associated_with	disease	0.65
Neurodegeneration	causes	disease	0.65
Ataxia	therapeutic_target	disease	0.65
Frontotemporal Dementia	therapeutic_target	disease	0.65
Als	associated_with	disease	0.65
Dementia	therapeutic_target	disease	0.65
Alzheimer	associated_with	disease	0.65
Parkinson	associated_with	disease	0.65
Als	interacts_with	disease	0.65
Neurodegeneration	inhibits	disease	0.65
Spinocerebellar Ataxia	expressed_in	disease	0.65
Ataxia	expressed_in	disease	0.65
Dementia	expressed_in	disease	0.65
Frontotemporal Dementia	expressed_in	disease	0.65
Spinocerebellar Ataxia	associated_with	disease	0.65
ALS	interacts_with	disease	0.65

Incoming (57)

Source	Relation	Type	Str
C9ORF72	upregulates	gene	0.85
C9ORF72	associated_with	gene	0.80
ATXN2	associated_with	gene	0.80
ALS	protects_against	gene	0.60
APOPTOSIS	inhibits	gene	0.60
AND	inhibits	gene	0.60
NEURODEGENERATION	therapeutic_target	gene	0.60
C9ORF72	activates	gene	0.60
MTOR	therapeutic_target	gene	0.60
C9ORF72	therapeutic_target	gene	0.60
ALS	associated_with	gene	0.60
DEMENTIA	therapeutic_target	gene	0.60
STAU2	associated_with	gene	0.60
ATXN2	inhibits	gene	0.60
HUNTINGTON	associated_with	gene	0.60
MTOR	interacts_with	gene	0.60
APOPTOSIS	regulates	gene	0.60
AUTOPHAGY	associated_with	gene	0.60
ALZHEIMER	associated_with	gene	0.60
PARKINSON	associated_with	gene	0.60
DEMENTIA	expressed_in	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	associated_with	gene	0.60
NEURODEGENERATIVE DISEASES	associated_with	gene	0.60
RNA	expressed_in	gene	0.60
C9ORF72	expressed_in	gene	0.60
AND	associated_with	gene	0.60
MTOR	expressed_in	gene	0.60
NEURODEGENERATION	causes	gene	0.60
ATXN2	causes	gene	0.60
RNA	interacts_with	gene	0.60
C9ORF72	causes	gene	0.60
AND	causes	gene	0.60
C9ORF72	inhibits	gene	0.60
MTOR	activates	gene	0.60
RNA	regulates	gene	0.60
amyotrophic lateral sclerosis	expressed_in	gene	0.50
Neurodegenerative Diseases	expressed_in	disease	0.50
Spinal Cord	expressed_in	cell_type	0.50
disease	expressed_in	disease	0.50
NEURODEGENERATIVE DISEASE	expressed_in	concept	0.50
ALZHEIMER	expressed_in	gene	0.50
PARKINSON	expressed_in	gene	0.50
HUNTINGTON	expressed_in	gene	0.50
Ataxia	expressed_in	disease	0.50
Fibroblast	expressed_in	cell_type	0.50
Spinocerebellar Ataxia	expressed_in	disease	0.50
ALZHEIMER'S	expressed_in	concept	0.50
PARKINSON'S	expressed_in	concept	0.50
FRONTOTEMPORAL	expressed_in	concept	0.50
HUNTINGTON'S	expressed_in	concept	0.50

Name	STAU1
Key Genes/Proteins	MTOR, P53
Related Diseases	Spinocerebellar Ataxia Type 2, Alzheimer'S Disease, Parkinson'S Disease

STAU1

Understanding Entity Pages

Wiki Pages (3)

RNA Stability and Decay

ELAVL3 Gene

MTOR Protein

Pathway Diagram

Outgoing (111)

Incoming (57)

Targeting Hypotheses (0)

Mentioning Analyses (0)

Experiments (0)

Related Papers (0)