Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CYP2C19: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| antidepressant drugs | modulates | drug | 0.85 |
| CYP2D6 | associated_with | gene | 0.60 |
| CYP3A4 | associated_with | gene | 0.60 |
| DRD2 | associated_with | gene | 0.60 |
| GCH1 | associated_with | gene | 0.60 |
| GPNMB | associated_with | gene | 0.60 |
| LRRK2 | associated_with | gene | 0.60 |
| NUCKS1 | associated_with | gene | 0.60 |
| SLC6A2 | associated_with | gene | 0.60 |
| SLC6A3 | associated_with | gene | 0.60 |
| SLC6A4 | associated_with | gene | 0.60 |
| SNCA | associated_with | gene | 0.60 |
| GABRA1 | associated_with | gene | 0.60 |
| GSTP1 | associated_with | gene | 0.60 |
| HMGCR | associated_with | gene | 0.60 |
| HTR2C | associated_with | gene | 0.60 |
| MAOB | associated_with | gene | 0.60 |
| MTHFR | associated_with | gene | 0.60 |
| NBEA | associated_with | gene | 0.60 |
| OPRM1 | associated_with | gene | 0.60 |
| SLC30A8 | associated_with | gene | 0.60 |
| CYP2D6 | regulates | gene | 0.60 |
| CYP3A4 | regulates | gene | 0.60 |
| PPAR | regulates | gene | 0.60 |
| SLC22A1 | regulates | gene | 0.60 |
| CYP2D6 | translocates_to | gene | 0.60 |
| CYP3A4 | translocates_to | gene | 0.60 |
| DRD2 | translocates_to | gene | 0.60 |
| GCH1 | translocates_to | gene | 0.60 |
| GPNMB | translocates_to | gene | 0.60 |
| LRRK2 | translocates_to | gene | 0.60 |
| NUCKS1 | translocates_to | gene | 0.60 |
| SLC6A2 | translocates_to | gene | 0.60 |
| SLC6A3 | translocates_to | gene | 0.60 |
| SLC6A4 | translocates_to | gene | 0.60 |
| SNCA | translocates_to | gene | 0.60 |
| depression | associated_with | disease | 0.60 |
| HTR2A | associated_with | gene | 0.60 |
| CYP2E1 | associated_with | gene | 0.60 |
| CYP3A5 | associated_with | gene | 0.60 |
| Alzheimer's disease | associated_with | disease | 0.60 |
| autophagy pathway | participates_in | pathway | 0.60 |
| CYP3A5 | regulates | gene | 0.60 |
| NR1I2 | regulates | gene | 0.60 |
| POR | regulates | gene | 0.60 |
| PCSK9 | associated_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:CYP2C19 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ABCB1 | associated_with | gene | 0.60 |
| APOE | associated_with | gene | 0.60 |
| ABCG2 | associated_with | gene | 0.60 |
| ADRA2A | associated_with | gene | 0.60 |
| ADRB2 | associated_with | gene | 0.60 |
| BCHE | associated_with | gene | 0.60 |
| CHAT | associated_with | gene | 0.60 |
| COMT | associated_with | gene | 0.60 |
| ABCB1 | regulates | gene | 0.60 |
| ACE | regulates | gene | 0.60 |
| CHAT | regulates | gene | 0.60 |
| CHRNA7 | regulates | gene | 0.60 |
| ABCB1 | translocates_to | gene | 0.60 |
| APOE | translocates_to | gene | 0.60 |
| CYP1A2 | associated_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:CYP2C19 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||