Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Infection: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet. View on Wiki →
| Associated Genes | INFLAMMATION, CANCER, OXIDATIVE STRESS, RAS, MICRORNAS, DNA, GENES, MTOR |
| KG Connections | 1721 knowledge graph edges |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
Knowledge base pages for this entity
graph TD
Infection["<b>Infection</b>"]
Autophagy["Autophagy"]
Infection -->|"regulates"| Autophagy
Als{"Als"}
Infection -->|"regulates"| Als
Viral_Infection{"Viral Infection"}
Infection -->|"activates"| Viral_Infection
Inflammation{"Inflammation"}
Infection -->|"activates"| Inflammation
Autoimmune{"Autoimmune"}
Infection -->|"activates"| Autoimmune
AUTOPHAGY(["AUTOPHAGY"])
AUTOPHAGY -->|"regulates"| Infection
APOPTOSIS(["APOPTOSIS"])
APOPTOSIS -->|"regulates"| Infection
CANCER(["CANCER"])
CANCER -->|"regulates"| Infection
DNA(["DNA"])
DNA -->|"regulates"| Infection
style Infection fill:#1a3a4a,stroke:#ef5350,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Autophagy | regulates | pathway | 1.00 |
| Als | regulates | disease | 1.00 |
| Als | treats | disease | 1.00 |
| Viral Infection | activates | disease | 1.00 |
| Inflammation | activates | disease | 1.00 |
| Autoimmune | activates | disease | 1.00 |
| Inflammation | associated_with | disease | 1.00 |
| Immune Response | regulates | pathway | 1.00 |
| Inflammation | regulates | disease | 1.00 |
| Als | associated_with | disease | 1.00 |
| Carcinoma | associated_with | disease | 1.00 |
| Inflammation | causes | disease | 1.00 |
| Innate Immunity | activates | pathway | 1.00 |
| Inflammation | implicated_in | disease | 1.00 |
| Cancer | associated_with | disease | 1.00 |
| Aging | associated_with | disease | 1.00 |
| Mtor | activates | pathway | 1.00 |
| Autophagy | activates | pathway | 1.00 |
| Immune Response | activates | pathway | 1.00 |
| Als | therapeutic_target | disease | 1.00 |
| Als | activates | disease | 1.00 |
| Neurodegeneration | activates | disease | 1.00 |
| Inflammation | therapeutic_target | disease | 1.00 |
| Inflammation | inhibits | disease | 1.00 |
| Sepsis | causes | disease | 1.00 |
| Immune Response | associated_with | pathway | 1.00 |
| Apoptosis | activates | pathway | 1.00 |
| Hepatitis | associated_with | disease | 1.00 |
| Neurodegeneration | associated_with | disease | 1.00 |
| Nf-Κb | activates | pathway | 1.00 |
| Viral Infection | associated_with | disease | 1.00 |
| Alzheimer | associated_with | disease | 1.00 |
| Neurodegeneration | regulates | disease | 1.00 |
| Inflammasome | activates | pathway | 1.00 |
| Inflammation | treats | disease | 1.00 |
| Immune Response | causes | pathway | 1.00 |
| Alzheimer | activates | disease | 1.00 |
| Als | implicated_in | disease | 1.00 |
| Als | causes | disease | 1.00 |
| Viral Infection | therapeutic_target | disease | 1.00 |
| Adaptive Immunity | regulates | pathway | 1.00 |
| Autophagy | implicated_in | pathway | 1.00 |
| Parkinson | associated_with | disease | 1.00 |
| Mapk | activates | pathway | 1.00 |
| Apoptosis | regulates | pathway | 1.00 |
| Oxidative Stress | associated_with | pathway | 1.00 |
| Immune Response | therapeutic_target | pathway | 1.00 |
| Autophagy | therapeutic_target | pathway | 1.00 |
| Autophagy | associated_with | pathway | 1.00 |
| Differentiation | regulates | pathway | 1.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AUTOPHAGY | regulates | gene | 1.00 |
| APOPTOSIS | regulates | gene | 1.00 |
| CANCER | regulates | gene | 1.00 |
| DNA | regulates | gene | 1.00 |
| Cancer | regulates | disease | 1.00 |
| INFLAMMATION | activates | gene | 1.00 |
| CANCER | activates | gene | 1.00 |
| Tumor | activates | disease | 1.00 |
| INFLAMMATION | associated_with | gene | 1.00 |
| CANCER | associated_with | gene | 1.00 |
| Cancer | associated_with | disease | 1.00 |
| INFLAMMATION | regulates | gene | 1.00 |
| OXIDATIVE STRESS | associated_with | gene | 1.00 |
| INFLAMMATION | causes | gene | 1.00 |
| CANCER | causes | gene | 1.00 |
| DNA | associated_with | gene | 1.00 |
| Tumor | associated_with | disease | 1.00 |
| CYTOKINES | activates | gene | 1.00 |
| INFLAMMATION | implicated_in | gene | 1.00 |
| GENES | associated_with | gene | 1.00 |
| AUTOPHAGY | activates | gene | 1.00 |
| ERK | activates | gene | 1.00 |
| MTOR | activates | gene | 1.00 |
| Tumor | regulates | disease | 1.00 |
| GENES | activates | gene | 1.00 |
| AKT | activates | gene | 1.00 |
| GENES | therapeutic_target | gene | 1.00 |
| NEURODEGENERATION | activates | gene | 1.00 |
| CYTOKINES | implicated_in | gene | 1.00 |
| INFLAMMATION | therapeutic_target | gene | 1.00 |
| Tumor | therapeutic_target | disease | 1.00 |
| GENES | regulates | gene | 1.00 |
| INFLAMMATION | contributes_to | gene | 1.00 |
| CANCER | implicated_in | gene | 1.00 |
| INFLAMMATION | inhibits | gene | 1.00 |
| ATP | activates | gene | 1.00 |
| APOPTOSIS | activates | gene | 1.00 |
| P62 | activates | gene | 1.00 |
| AUTOPHAGY | therapeutic_target | gene | 1.00 |
| NEURODEGENERATION | associated_with | gene | 1.00 |
| NF-ΚB | activates | gene | 1.00 |
| Cancer | activates | disease | 1.00 |
| ALZHEIMER | associated_with | gene | 1.00 |
| VIRAL INFECTIONS | associated_with | gene | 1.00 |
| AUTOPHAGY | associated_with | gene | 1.00 |
| AGING | associated_with | gene | 1.00 |
| NEURODEGENERATION | regulates | gene | 1.00 |
| DNA | activates | gene | 1.00 |
| INFLAMMATION | treats | gene | 1.00 |
| NEUROINFLAMMATION | activates | gene | 1.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neuroinflammation | 2026-04-14 | 2 hypotheses Top: 0.499
neuroinflammation | 2026-04-13 | 0 hypotheses
neuroimmunology | 2026-04-11 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||