Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NUCLEUS ACCUMBENS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NUCLEUS ACCUMBENS |
| Key Genes/Proteins | CHRNA7, APOE, TAU |
| Related Diseases | GLUTAMATE, SCHIZOPHRENIA |
Knowledge base pages for this entity
graph TD
NUCLEUS_ACCUMBENS["NUCLEUS ACCUMBENS"]
NUCLEUS_ACCUMBENS -->|"inhibits"| SCHIZOPHRENIA["SCHIZOPHRENIA"]
NUCLEUS_ACCUMBENS -->|"inhibits"| STRIATUM["STRIATUM"]
AND["AND"] -->|"expressed in"| NUCLEUS_ACCUMBENS
AADC["AADC"] -->|"expressed in"| NUCLEUS_ACCUMBENS
NEURON["NEURON"] -->|"expressed in"| NUCLEUS_ACCUMBENS
TAAR1["TAAR1"] -->|"expressed in"| NUCLEUS_ACCUMBENS
CHRNA7["CHRNA7"] -->|"expressed in"| NUCLEUS_ACCUMBENS
RNA["RNA"] -->|"expressed in"| NUCLEUS_ACCUMBENS
GAIN["GAIN"] -->|"expressed in"| NUCLEUS_ACCUMBENS
CSF2["CSF2"] -->|"expressed in"| NUCLEUS_ACCUMBENS| Target | Relation | Type | Str |
|---|---|---|---|
| STRIATUM | activates | brain_region | 0.65 |
| ASTROCYTES | associated_with | cell_type | 0.50 |
| NEURONS | associated_with | cell_type | 0.45 |
| NEURON | associated_with | cell_type | 0.45 |
| CHRNA7 | associated_with | gene | 0.45 |
| GLUTAMATE | associated_with | phenotype | 0.45 |
| APOE | associated_with | gene | 0.45 |
| TAU | associated_with | protein | 0.45 |
| SCHIZOPHRENIA | co_discussed | disease | 0.40 |
| STRIATUM | co_discussed | brain_region | 0.40 |
| THALAMUS | co_discussed | brain_region | 0.40 |
| SCHIZOPHRENIA | inhibits | disease | 0.35 |
| STRIATUM | inhibits | brain_region | 0.35 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GLUTAMATE | interacts_with | phenotype | 0.65 |
| ASTROCYTES | implicated_in | cell_type | 0.55 |
| NAC | associated_with | drug | 0.45 |
| NEURON | co_discussed | cell_type | 0.40 |
| NEURONS | co_discussed | cell_type | 0.40 |
| GLUTAMATERGIC | co_discussed | cell_type | 0.40 |
| HYPOTHALAMUS | co_discussed | brain_region | 0.40 |
| NEURON | inhibits | cell_type | 0.35 |
| HYPOTHALAMUS | regulates | brain_region | 0.35 |
| NEURON | regulates | cell_type | 0.35 |
| CHRNA7 | regulates | gene | 0.35 |
| N-ACETYLCYSTEINE | regulates | drug | 0.35 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||