concept

GLUTAMATERGIC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GLUTAMATERGIC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

78Connections

0Hypotheses

0Analyses

43Outgoing

35Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	GLUTAMATERGIC
Key Genes/Proteins	TAU, BIN1
Related Diseases	TUMOR
Linked Hypotheses	1 hypotheses

Wiki Pages (20)

Knowledge base pages for this entity

AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery Alternatives

therapeutic · 15567 words

→

Pathway Diagram

graph TD
    GLUTAMATERGIC["GLUTAMATERGIC"]
    GLUTAMATERGIC -->|"inhibits"| PROTEIN_AGGREGATION["PROTEIN AGGREGATION"]
    GLUTAMATERGIC -->|"inhibits"| UNFOLDED_PROTEIN_RESPONSE["UNFOLDED PROTEIN RESPONSE"]
    GLUTAMATERGIC -->|"expressed in"| NEURON["NEURON"]
    GLUTAMATERGIC -->|"expressed in"| NEURONS["NEURONS"]
    GLUTAMATERGIC -->|"expressed in"| OLIGODENDROCYTE["OLIGODENDROCYTE"]
    GLUTAMATERGIC -->|"expressed in"| OLIGODENDROCYTES["OLIGODENDROCYTES"]
    AUTOPHAGY["AUTOPHAGY"] -->|"inhibits"| GLUTAMATERGIC
    DOPAMINERGIC["DOPAMINERGIC"] -->|"causes"| GLUTAMATERGIC
    BIN1["BIN1"] -->|"regulates"| GLUTAMATERGIC
    CA1["CA1"] -->|"inhibits"| GLUTAMATERGIC
    GABAERGIC["GABAERGIC"] -->|"inhibits"| GLUTAMATERGIC
    CORTEX["CORTEX"] -->|"activates"| GLUTAMATERGIC

Outgoing (43)

Target	Relation	Type	Str
NEURON	expressed_in	cell_type	0.65
NEURONS	expressed_in	cell_type	0.65
OLIGODENDROCYTE	expressed_in	cell_type	0.65
OLIGODENDROCYTES	expressed_in	cell_type	0.65
NEURON	transports	cell_type	0.65
NEURONS	transports	cell_type	0.65
NEURON	regulates	cell_type	0.65
NEURONS	regulates	cell_type	0.65
NEURON	inhibits	cell_type	0.65
NEURONS	inhibits	cell_type	0.65
TUMOR	activates	disease	0.65
TAU	regulates	gene	0.65
TAU	causes	gene	0.65
HYPOTHALAMUS	causes	brain_region	0.60
NEURON	causes	cell_type	0.60
NEURONS	causes	cell_type	0.60
STROKE	causes	disease	0.60
THALAMUS	causes	brain_region	0.60
MOTOR NEURON	causes	cell_type	0.60
NEURODEGENERATION	promotes	disease	0.60
SYNAPTIC TRANSMISSION	regulates	biological_process	0.60
HIPPOCAMPUS	biomarker_for	brain_region	0.60
NEURON	promotes	cell_type	0.60
NEURONS	promotes	cell_type	0.60
NEURON	associated_with	cell_type	0.60
NEURONS	associated_with	cell_type	0.60
NEURON	contributes_to	cell_type	0.60
STROKE	contributes_to	disease	0.60
HIPPOCAMPUS	causes	brain_region	0.60
NEURONS	contributes_to	cell_type	0.60
SCHIZOPHRENIA	contributes_to	disease	0.60
MAPT	causes	gene	0.60
MAPT	activates	gene	0.60
MAPT	regulates	gene	0.60
SYNAPSE	co_discussed	entity	0.50
NEURON	co_discussed	cell_type	0.40
NEURONS	co_discussed	cell_type	0.40
THALAMUS	co_discussed	brain_region	0.40
HYPOTHALAMUS	co_discussed	brain_region	0.40
NUCLEUS ACCUMBENS	co_discussed	brain_region	0.40
WHITE MATTER	co_discussed	brain_region	0.40
NEURODEGENERATION	co_discussed	disease	0.40
SCHIZOPHRENIA	co_discussed	disease	0.40

Incoming (35)

Source	Relation	Type	Str
DOPAMINERGIC	causes	cell_type	0.65
BIN1	regulates	gene	0.65
BIN1	causes	gene	0.65
BIN1	transports	gene	0.65
CA1	inhibits	brain_region	0.65
GABAERGIC	inhibits	cell_type	0.65
CORTEX	activates	brain_region	0.65
FRONTOTEMPORAL DEMENTIA	causes	disease	0.65
DEPRESSION	inhibits	disease	0.65
AMPK	associated_with	gene	0.65
ALS	causes	disease	0.60
DEPRESSION	promotes	disease	0.60
ASTROCYTE	regulates	cell_type	0.60
ASTROCYTES	regulates	cell_type	0.60
CHOLINERGIC	biomarker_for	cell_type	0.60
GABAERGIC	biomarker_for	cell_type	0.60
GABAERGIC	associated_with	cell_type	0.60
DOPAMINERGIC	contributes_to	cell_type	0.60
DRD2	contributes_to	gene	0.60
DEMENTIA	causes	disease	0.60
FRONTOTEMPORAL	causes	disease	0.60
FTD	causes	disease	0.60
CLU	regulates	gene	0.60
ALZHEIMER	regulates	disease	0.60
ALZHEIMER'S	regulates	disease	0.60
ALZHEIMER'S DISEASE	regulates	disease	0.60
ANXIETY	causes	disease	0.60
DEPRESSION	targets	disease	0.60
GABAERGIC	targets	cell_type	0.60
GLUTAMATE	co_discussed	entity	0.50
GABAERGIC	co_discussed	cell_type	0.40
FTD	co_discussed	disease	0.40
BDNF	co_discussed	gene	0.40
DOPAMINERGIC	co_discussed	cell_type	0.40
DEPRESSION	co_discussed	disease	0.40

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

GLUTAMATERGIC

Understanding Entity Pages

Wiki Pages (20)

AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery Alternatives

Section 148: Advanced Nutritional Biochemistry in CBS/PSP

Myoclonus and Cortical Hyperexcitability in Corticobasal Syndrome

nimodipine-als

NPM1 Gene

Neurons — Cell Type Hierarchy

GRIA3 Gene

NTF4 Protein

CNTN5 — Contactin 5

CLCN10 — Chloride Voltage-Gated Channel 10

rasagiline

Tau Spreading Mechanism

ncam2

gabaergic-dysfunction

CNTN6 — Contactin 6

dendritic-spines

Rapamycin ALS Trial - mTOR Inhibition for Amyotrophic Lateral Sclerosis

Spinal Cord Dorsal Horn Neurons