Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NMDA RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | NMDA RECEPTOR |
| Molecular Weight | 220 kDa |
| Pathways | Neurodegeneration |
| Associated Diseases | Alzheimer |
| Interactions | NMDA, AMPA RECEPTOR |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
NMDA_RECEPTOR["NMDA RECEPTOR"]
NMDA_RECEPTOR -->|"involved_in"| Neurodegeneration["Neurodegeneration"]
NMDA_RECEPTOR -->|"mediates"| Synaptic_Plasticity["Synaptic Plasticity"]
NMDA_RECEPTOR -->|"modulates"| ARHGEF7["ARHGEF7"]
NMDA_RECEPTOR -->|"activates"| Als["Als"]
NMDA_RECEPTOR -->|"activates"| Multiple_Sclerosis["Multiple Sclerosis"]
Memantine["Memantine"] -->|"inhibits"| NMDA_RECEPTOR
Compound_A["Compound A"] -->|"inhibits"| NMDA_RECEPTOR
Compound_B["Compound B"] -->|"inhibits"| NMDA_RECEPTOR
Compound_C["Compound C"] -->|"inhibits"| NMDA_RECEPTOR
RAC1["RAC1"] -->|"regulates"| NMDA_RECEPTOR
SYNAPSE["SYNAPSE"] -->|"regulates"| NMDA_RECEPTOR
ARHGEF7 -->|"regulates"| NMDA_RECEPTOR
P53["P53"] -->|"inhibits"| NMDA_RECEPTOR| Target | Relation | Type | Str |
|---|---|---|---|
| GLUTAMATE | activates | concept | 0.50 |
| Synaptic Plasticity | regulates | pathway | 0.50 |
| GLUTAMATE | associated_with | concept | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| NMDA | activates | protein | 0.50 |
| AMPA RECEPTOR | activates | protein | 0.50 |
| NMDA | regulates | protein | 0.50 |
| VGLUT1 | associated_with | gene | 0.50 |
| NMDA | associated_with | protein | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||