SciDEX — PREFRONTAL CORTEX

graph TD
    PREFRONTAL_CORTEX["PREFRONTAL CORTEX"]
    PREFRONTAL_CORTEX -->|"interacts"| Cognition["Cognition"]
    PREFRONTAL_CORTEX -->|"treats"| depression["depression"]
    Cognition -->|"interacts"| PREFRONTAL_CORTEX
    TMS["TMS"] -->|"regulates"| PREFRONTAL_CORTEX
    BDNF["BDNF"] -->|"expressed in"| PREFRONTAL_CORTEX
    PER["PER"] -->|"expressed in"| PREFRONTAL_CORTEX
    CANCER["CANCER"] -->|"expressed in"| PREFRONTAL_CORTEX
    CNO["CNO"] -->|"expressed in"| PREFRONTAL_CORTEX
    PHAGOCYTOSIS["PHAGOCYTOSIS"] -->|"expressed in"| PREFRONTAL_CORTEX
    HSPA1A["HSPA1A"] -->|"expressed in"| PREFRONTAL_CORTEX
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"expressed in"| PREFRONTAL_CORTEX
    MICROGLIA["MICROGLIA"] -->|"expressed in"| PREFRONTAL_CORTEX

Outgoing (99)

Target	Relation	Type	Str
SUBSTANTIA NIGRA	causes	brain_region	0.65
GENE EXPRESSION	inhibits	concept	0.50
NUCLEUS	inhibits	concept	0.50
NUCLEUS	regulates	concept	0.50
Proteins	regulates	protein	0.50
NUCLEUS	associated_with	concept	0.50
AMYGDALA	associated_with	concept	0.50
AMYGDALA	regulates	concept	0.50
NUCLEUS	expressed_in	concept	0.50
INTERNEURONS	activates	concept	0.50
INTERNEURONS	inhibits	concept	0.50
FRONTAL	activates	concept	0.50
GENE EXPRESSION	expressed_in	concept	0.50
SEROTONIN	activates	concept	0.50
GRAY MATTER	interacts_with	concept	0.50
GRAY MATTER	associated_with	concept	0.50
PURKINJE CELLS	associated_with	cell_type	0.50
TET2	associated_with	gene	0.50
NEUROGENESIS	associated_with	phenotype	0.50
GABA	associated_with	phenotype	0.50
TH	associated_with	gene	0.50
C9orf72	associated_with	gene	0.45
TDP-43	associated_with	gene	0.45
SOD1	associated_with	gene	0.45
AMYLOID-BETA	associated_with	protein	0.45
MEMORY LOSS	associated_with	phenotype	0.45
NEURONS	associated_with	cell_type	0.45
GLUTAMATE	associated_with	phenotype	0.45
BIPOLAR DISORDER	associated_with	disease	0.45
SEROTONIN	associated_with	phenotype	0.45
ACETYLCHOLINE	associated_with	phenotype	0.45
PSILOCYBIN	associated_with	drug	0.45
INTERNEURONS	associated_with	cell_type	0.45
CHRNA7	associated_with	gene	0.45
APOE	associated_with	gene	0.45
BERBERINE	associated_with	drug	0.45
CYTOKINES	associated_with	phenotype	0.45
NLRP3	associated_with	gene	0.45
BIN1	associated_with	gene	0.45
PYROPTOSIS	associated_with	phenotype	0.45
SYNAPTIC LOSS	associated_with	phenotype	0.45
RAPAMYCIN	associated_with	drug	0.45
LAMP1	associated_with	gene	0.45
OXIDATIVE STRESS	associated_with	phenotype	0.45
HMGB1	associated_with	gene	0.45
TLR4	associated_with	gene	0.45
RESVERATROL	associated_with	drug	0.45
METFORMIN	associated_with	drug	0.45
AMPK	associated_with	gene	0.45
BDNF	associated_with	gene	0.45

Incoming (336)

Source	Relation	Type	Str
ALZHEIMER'S DISEASE	associated_with	disease	1.00
PARKINSON'S DISEASE	associated_with	disease	0.82
ASTROCYTES	associated_with	cell_type	0.82
MICROGLIA	associated_with	cell_type	0.74
BDNF	associated_with	gene	0.74
AMYLOID	associated_with	protein	0.74
INFLAMMATION	causes	phenotype	0.70
INFLAMMATION	activates	phenotype	0.70
APP	regulates	gene	0.70
HIPPOCAMPUS	contributes_to	brain_region	0.65
CORTEX	impairs	brain_region	0.65
CORTEX	contributes_to	brain_region	0.65
C9ORF72	regulates	gene	0.65
CORTEX	transports	brain_region	0.65
CORTEX	biomarker_for	brain_region	0.65
CORTEX	targets	brain_region	0.65
CORTEX	causes	brain_region	0.65
DOPAMINERGIC	causes	cell_type	0.65
NEURON	contributes_to	cell_type	0.65
CORTEX	mediates	brain_region	0.65
DRD2	mediates	gene	0.65
DEPRESSION	regulates	disease	0.65
APOPTOSIS	regulates	phenotype	0.65
NEURONS	causes	cell_type	0.65
BDNF	phosphorylates	gene	0.65
FERROPTOSIS	causes	phenotype	0.65
TAU	associated_with	protein	0.64
ALS	regulates	disease	0.58
FUS	regulates	gene	0.58
APOPTOSIS	inhibits	process	0.58
IL-6	associated_with	gene	0.56
CORTEX	participates_in	brain_region	0.55
NEURON	expressed_in	cell_type	0.50
HIPPOCAMPUS	activates	brain_region	0.50
BDNF	activates	gene	0.50
NEURON	regulates	cell_type	0.50
CORTEX	regulates	brain_region	0.50
CORTEX	expressed_in	brain_region	0.50
Cortex	activates	brain_region	0.50
Cortex	associated_with	brain_region	0.50
Hippocampus	associated_with	entity	0.50
DEMENTIA	inhibits	gene	0.50
Cortex	inhibits	brain_region	0.50
Cognitive Impairment	inhibits	phenotype	0.50
Cortex	regulates	brain_region	0.50
DOPAMINERGIC	regulates	concept	0.50
DOPAMINE	regulates	concept	0.50
Cortex	expressed_in	brain_region	0.50
NEURONS	expressed_in	concept	0.50
late	regulates	disease	0.50

Name	PREFRONTAL CORTEX
Key Genes/Proteins	AMYLOID, APP, C9ORF72
Related Diseases	ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, INFLAMMATION

PREFRONTAL CORTEX

Understanding Entity Pages

Wiki Pages (20)

cbs-psp-daily-action-plan

Clinical Management Guide for CBS/PSP

Progressive Supranuclear Palsy (PSP)

Sleep and Circadian Dysfunction in Alzheimer's Disease

Atypical Parkinsonism

Pathway Diagram

Outgoing (99)

Incoming (336)

Targeting Hypotheses (0)

Mentioning Analyses (0)

Related Papers (0)

PREFRONTAL CORTEX

Understanding Entity Pages

Wiki Pages (20)

cbs-psp-daily-action-plan

Clinical Management Guide for CBS/PSP

Progressive Supranuclear Palsy (PSP)

Sleep and Circadian Dysfunction in Alzheimer's Disease

Atypical Parkinsonism

Device Therapies Comparison for CBS/PSP

Frontotemporal Dementia (FTD) Mechanistic Pathway

GRIA3 Gene

williams-syndrome

GSK-3β in Neurodegeneration

CNTN5 — Contactin 5

cerebral-cortical-vasal-neurons

gabaergic-dysfunction

CNTN6 — Contactin 6

Huntington's Disease

Vascular Cognitive Impairment (VCI)

CNTN4 — Contactin 4

Cerebellar Function

nf1-protein

psp-tauopathy

Pathway Diagram

Outgoing (99)

Incoming (336)

Targeting Hypotheses (0)

Mentioning Analyses (0)

Related Papers (0)