PCK1

Understanding Entity Pages

This page aggregates everything SciDEX knows about PCK1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PCK1 is a concept in neurodegeneration research. Key relationships include: therapeutic target, activates, interacts with. Associated with ALS, Aging, Als. Connected to 59 entities in the SciDEX knowledge graph.

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graph TD
    PCK1["<b>PCK1</b>"]
    PCK1 -->|"activates"| Als["Als"]
    PCK1 -->|"activates"| Aging["Aging"]
    PCK1 -->|"regulates"| Ms["Ms"]
    PCK1 -.protects against.-> Fibrosis["Fibrosis"]
    PCK1 -->|"activates"| Hepatitis["Hepatitis"]
    PCK1 -->|"activates"| Carcinoma["Carcinoma"]
    PCK1 -->|"activates"| Cancer["Cancer"]
    PCK1 -->|"interacts"| Tumor["Tumor"]
    PCK1 -->|"target for"| Alzheimer["Alzheimer"]
    CD8["CD8"] -->|"regulates"| PCK1
    PER["PER"] -->|"interacts"| PCK1
    CD36["CD36"] -->|"interacts"| PCK1
    CANCER["CANCER"] -->|"interacts"| PCK1
    LPL["LPL"] -->|"interacts"| PCK1
    PPARGC1A["PPARGC1A"] -->|"interacts"| PCK1
    PPARG["PPARG"] -->|"interacts"| PCK1
    CXCL1["CXCL1"] -->|"target for"| PCK1
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"] -->|"target for"| PCK1
    SOCS3["SOCS3"] -->|"target for"| PCK1
    IL6["IL6"] -->|"target for"| PCK1
    MICROGLIA["MICROGLIA"] -->|"target for"| PCK1