SciDEX — CLDN2

Understanding Entity Pages

This page aggregates everything SciDEX knows about CLDN2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Outgoing (37)

Target	Relation	Type	Str
MAPK signaling	participates_in	pathway	0.70
CRC	associated_with	disease	0.60
ERN1	activates	gene	0.60
IRGM1	activates	gene	0.60
LC3	activates	gene	0.60
MELK	activates	gene	0.60
MTOR	activates	gene	0.60
NLRP3	activates	gene	0.60
NOD2	activates	gene	0.60
PI3K	activates	gene	0.60
PYCARD	activates	gene	0.60
RALGAPA2	activates	gene	0.60
RIPK2	activates	gene	0.60
RIPK3	activates	gene	0.60
SMARCA4	activates	gene	0.60
SNF	activates	gene	0.60
SQSTM1	activates	gene	0.60
STAT3	activates	gene	0.60
SWI	activates	gene	0.60
TNF	activates	gene	0.60
TNFA	activates	gene	0.60
ULK1	activates	gene	0.60
cancer	activates	disease	0.60
WNT	activates	gene	0.60
autophagy pathway	participates_in	pathway	0.60
apoptosis pathway	participates_in	pathway	0.60
IKK	activates	gene	0.60
MAP1LC3	activates	gene	0.60
MAPK	activates	gene	0.60
NLR	activates	gene	0.60
NRBF2	activates	gene	0.60
oxidative stress response	participates_in	pathway	0.60
necroptosis	participates_in	pathway	0.60
ROS	activates	gene	0.60
PI3K-AKT-mTOR signaling	participates_in	pathway	0.60
stem cells	expressed_in	cell_type	0.55
benchmark_ot_ad_answer_key:CLDN2	data_in	dataset_row	0.00

Incoming (19)

Source	Relation	Type	Str
AKT1	activates	gene	0.60
AMBRA1	activates	gene	0.60
APC	activates	gene	0.60
ATF6	activates	gene	0.60
BECN1	activates	gene	0.60
CALCOCO2	activates	gene	0.60
CASP3	activates	gene	0.60
CFTR	activates	gene	0.60
CGAS	activates	gene	0.60
ASC	activates	gene	0.60
BRG1	activates	gene	0.60
AKT1S1	activates	gene	0.60
AMPK	activates	gene	0.60
ATG	activates	gene	0.60
CDH1	activates	gene	0.60
CCDC50	activates	gene	0.60
rapamycin	targets	drug	0.60
ATP	activates	gene	0.60
benchmark_ot_ad_answer_key:CLDN2	data_in	dataset_row	0.00

CLDN2

Understanding Entity Pages

Outgoing (37)

Incoming (19)

Targeting Hypotheses (0)

Mentioning Analyses (0)

Related Papers (0)