concept

PEROXISOME

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PEROXISOME: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

142Connections
0Hypotheses
0Analyses
0Outgoing
50Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NamePEROXISOME
Key Genes/ProteinsPGC-1Α, PPAR, ACTB, PPARGC1A, RPS6, SQSTM1

Wiki Pages (21)

Knowledge base pages for this entity

Canonical Page

payload-peroxisome-restoration-therapy

general · 997 words

Progressive Supranuclear Palsy (PSP)

disease · 12907 words

CBS/PSP Treatment Rankings

therapeutic · 5434 words

NTF4 Protein

protein · 5111 words

Mitochondrial Quality Control

mechanism · 5069 words

Mitochondrial Dysfunction in Parkinson's Disease

mechanism · 4972 words

Pathway Diagram

graph TD
    PEROXISOME["PEROXISOME"]
    PEROXISOME -->|"activates"| RAPAMYCIN["RAPAMYCIN"]
    PEROXISOME -->|"activates"| PGC_1ALPHA["PGC-1ALPHA"]
    PEROXISOME -->|"activates"| SQSTM1["SQSTM1"]
    PEROXISOME -->|"activates"| RAS["RAS"]
    PEROXISOME -->|"activates"| TFEB["TFEB"]
    PEROXISOME -->|"activates"| STEM_CELLS["STEM CELLS"]
    PEROXISOME -->|"activates"| PI3K["PI3K"]
    PEROXISOME -->|"activates"| ULK1["ULK1"]
    AUTOPHAGY["AUTOPHAGY"] -->|"activates"| PEROXISOME
    MTOR["MTOR"] -->|"activates"| PEROXISOME
    AMPK["AMPK"] -->|"activates"| PEROXISOME
    LIPID_METABOLISM["LIPID METABOLISM"] -->|"activates"| PEROXISOME
    LYSOSOME["LYSOSOME"] -->|"activates"| PEROXISOME
    BECN1["BECN1"] -->|"activates"| PEROXISOME
    NUCLEUS["NUCLEUS"] -->|"activates"| PEROXISOME
    LAMP1["LAMP1"] -->|"activates"| PEROXISOME

Outgoing (0)

TargetRelationTypeStr
No outgoing edges

Incoming (142)

SourceRelationTypeStr
PGC-1Αactivatesprotein0.50
PPARactivatesprotein0.50
GLUT4activatesconcept0.50
GENE EXPRESSIONactivatesconcept0.50
ACTBactivatesgene0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found