RPS6

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPS6: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Gene page for RPS6 (Ribosomal Protein S6), a component of the 40S ribosomal subunit, substrate of S6 kinases, and associated with Noonan syndrome, cancer, and mTOR signaling.

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flowchart TD
    RPS6["RPS6"] -->|"activates"| Metabolic_Syndrome["Metabolic Syndrome"]
    RPS6["RPS6"] -->|"regulates"| Ischemia["Ischemia"]
    RPS6["RPS6"] -->|"regulates"| Ms["Ms"]
    RPS6["RPS6"] -->|"associated with"| Metabolic_Syndrome["Metabolic Syndrome"]
    RPS6["RPS6"] -->|"activates"| Lysosomal_Degradation["Lysosomal Degradation"]
    RPS6["RPS6"] -->|"regulates"| Mtor["Mtor"]
    RPS6["RPS6"] -->|"activates"| Lipid_Metabolism["Lipid Metabolism"]
    RPS6["RPS6"] -->|"regulates"| Autophagy["Autophagy"]
    RPS6["RPS6"] -->|"regulates"| MAP1LC3B["MAP1LC3B"]
    RPS6["RPS6"] -->|"regulates"| MTOR["MTOR"]
    RPS6["RPS6"] -->|"regulates"| CTSD["CTSD"]
    RPS6["RPS6"] -->|"regulates"| LAMP1["LAMP1"]
    style RPS6 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style Metabolic_Syndrome fill:#ef5350,stroke:#333,color:#e0e0e0
    style Ischemia fill:#ef5350,stroke:#333,color:#e0e0e0
    style Ms fill:#ef5350,stroke:#333,color:#e0e0e0
    style Lysosomal_Degradation fill:#1b5e20,stroke:#333,color:#e0e0e0
    style Mtor fill:#1b5e20,stroke:#333,color:#e0e0e0
    style Lipid_Metabolism fill:#1b5e20,stroke:#333,color:#e0e0e0
    style Autophagy fill:#1b5e20,stroke:#333,color:#e0e0e0
    style MAP1LC3B fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style MTOR fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style CTSD fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style LAMP1 fill:#4a1a6b,stroke:#333,color:#e0e0e0