pathway

Receptor Tyrosine Kinase

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Receptor Tyrosine Kinase: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

140Connections

0Hypotheses

1Analyses

2Outgoing

50Incoming

No summary available yet. View on Wiki →

🔀 Pathway Info

Name	Receptor Tyrosine Kinase
Key Genes/Proteins	AKT, RAS, ERK, CANCER, PI3K, APOPTOSIS
Related Diseases	Als, Cancer

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    AKT["AKT"] -->|"activates"| Receptor_Tyrosine_Kinase["Receptor Tyrosine Kinase"]
    RAS["RAS"] -->|"activates"| Receptor_Tyrosine_Kinase["Receptor Tyrosine Kinase"]
    Als["Als"] -->|"activates"| Receptor_Tyrosine_Kinase["Receptor Tyrosine Kinase"]
    ERK["ERK"] -->|"activates"| Receptor_Tyrosine_Kinase["Receptor Tyrosine Kinase"]
    style Receptor_Tyrosine_Kinase fill:#1b5e20,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (2)

Target	Relation	Type	Str
Proteins	activates	protein	0.50
Proteins	associated_with	protein	0.50

Incoming (138)

Source	Relation	Type	Str
AKT	activates	gene	1.00
RAS	activates	gene	1.00
Als	activates	disease	1.00
ERK	activates	gene	1.00
Cancer	activates	disease	1.00
CANCER	activates	gene	0.90
PI3K	activates	gene	0.80
Cancer	therapeutic_target	disease	0.80
Als	therapeutic_target	disease	0.80
APOPTOSIS	activates	gene	0.80
CANCER	regulates	gene	0.80
Cancer	regulates	disease	0.80
ERK	inhibits	gene	0.70
CANCER	therapeutic_target	gene	0.70
EGF	activates	gene	0.70
Tumor	therapeutic_target	disease	0.70
GENES	therapeutic_target	gene	0.70
Melanoma	therapeutic_target	disease	0.70
Als	regulates	disease	0.70
Tumor	inhibits	disease	0.70
Carcinoma	activates	disease	0.70
Tumor	activates	disease	0.70
AKT	inhibits	gene	0.60
PI3K	inhibits	gene	0.60
RAS	expressed_in	gene	0.60
Leukemia	expressed_in	disease	0.60
Als	expressed_in	disease	0.60
APOPTOSIS	contributes_to	gene	0.60
CANCER	contributes_to	gene	0.60
PIK3CA	contributes_to	gene	0.60
DNA	contributes_to	gene	0.60
MTOR	contributes_to	gene	0.60
Tumor	contributes_to	disease	0.60
Breast Cancer	contributes_to	disease	0.60
Cancer	contributes_to	disease	0.60
PTEN	activates	gene	0.60
PI3K	therapeutic_target	gene	0.60
SRC	activates	gene	0.60
APOPTOSIS	therapeutic_target	gene	0.60
UBIQUITIN	activates	gene	0.60
BCL-2	activates	gene	0.60
RAS	inhibits	gene	0.60
CANCER	inhibits	gene	0.60
Neuroblastoma	inhibits	disease	0.60
Breast Cancer	inhibits	disease	0.60
Cancer	inhibits	disease	0.60
Als	inhibits	disease	0.60
CREB	activates	gene	0.60
NEURODEGENERATION	activates	gene	0.60
Neurodegeneration	activates	disease	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

Quantitative proteomics of the aging synapse in early Alzheimer disease

neurodegeneration | 2026-04-04 | 0 hypotheses

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Receptor Tyrosine Kinase

Understanding Entity Pages

Wiki Pages (20)

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